Zinc halide complexes of imidazolidine-2-thione and its derivatives: X-ray structures, solid state, solution NMR and antimicrobial activity studies

Mohammed Fettouhi; Mohamed I.M. Wazeer; Anvarhusein A. Isab

doi:10.1080/00958970600780965

Zinc halide complexes of imidazolidine-2-thione and its derivatives: X-ray structures, solid state, solution NMR and antimicrobial activity studies

Mohammed Fettouhi, Mohamed I.M. Wazeer, Anvarhusein A. Isab^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The preparation and characterization of zinc complexes of formula ZnL2X2 (X = Cl and Br), with L = 1,3-diazinane-2-thione (Diaz), 1,3-diazipane-2-thione (Diap), imidazolidine-2-thione (Imt) and its methyl and n-propyl substituted derivatives, are described. The complexes dichlorobis(1-methylimidazolidine-2- thione-S)-zinc(II) (1) and dichlorobis(1-propylimidazolidine-2-thione-S)- zinc(II) (2) have been characterized by single-crystal X-ray methods. Both complexes adopt distorted tetrahedral geometry. Only intramolecular hydrogen bonding interactions are observed in 1 and 2. Solution and solid state 13C NMR show a significant shift of the C=S carbon resonance of the ligands, while other resonances are relatively unaffected, indicating that most likely the solid state structure is maintained in solution. Antimicrobial activity studies of the free ligands and their complexes show that ligands exhibit substantial antibacterial activities compared to the complexes.

Original language	English
Pages (from-to)	369-377
Number of pages	9
Journal	Journal of Coordination Chemistry
Volume	60
Issue number	4
DOIs	https://doi.org/10.1080/00958970600780965
State	Published - 2007

Bibliographical note

Funding Information:
We gratefully acknowledge the King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia, for financial support through research project CY/NMR STUDY/277.

Keywords

Antibacterial activity
Crystal structure
Imidazolidine-2-thione
MAS NMR
Zinc

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Materials Chemistry

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10.1080/00958970600780965

Cite this

@article{a26f34a910be4e7dad115b66eadf4007,

title = "Zinc halide complexes of imidazolidine-2-thione and its derivatives: X-ray structures, solid state, solution NMR and antimicrobial activity studies",

abstract = "The preparation and characterization of zinc complexes of formula ZnL2X2 (X = Cl and Br), with L = 1,3-diazinane-2-thione (Diaz), 1,3-diazipane-2-thione (Diap), imidazolidine-2-thione (Imt) and its methyl and n-propyl substituted derivatives, are described. The complexes dichlorobis(1-methylimidazolidine-2- thione-S)-zinc(II) (1) and dichlorobis(1-propylimidazolidine-2-thione-S)- zinc(II) (2) have been characterized by single-crystal X-ray methods. Both complexes adopt distorted tetrahedral geometry. Only intramolecular hydrogen bonding interactions are observed in 1 and 2. Solution and solid state 13C NMR show a significant shift of the C=S carbon resonance of the ligands, while other resonances are relatively unaffected, indicating that most likely the solid state structure is maintained in solution. Antimicrobial activity studies of the free ligands and their complexes show that ligands exhibit substantial antibacterial activities compared to the complexes.",

keywords = "Antibacterial activity, Crystal structure, Imidazolidine-2-thione, MAS NMR, Zinc",

author = "Mohammed Fettouhi and Wazeer, \{Mohamed I.M.\} and Isab, \{Anvarhusein A.\}",

note = "Funding Information: We gratefully acknowledge the King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia, for financial support through research project CY/NMR STUDY/277.",

year = "2007",

doi = "10.1080/00958970600780965",

language = "English",

volume = "60",

pages = "369--377",

journal = "Journal of Coordination Chemistry",

issn = "0095-8972",

number = "4",

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T2 - X-ray structures, solid state, solution NMR and antimicrobial activity studies

AU - Fettouhi, Mohammed

AU - Wazeer, Mohamed I.M.

AU - Isab, Anvarhusein A.

N1 - Funding Information: We gratefully acknowledge the King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia, for financial support through research project CY/NMR STUDY/277.

PY - 2007

Y1 - 2007

N2 - The preparation and characterization of zinc complexes of formula ZnL2X2 (X = Cl and Br), with L = 1,3-diazinane-2-thione (Diaz), 1,3-diazipane-2-thione (Diap), imidazolidine-2-thione (Imt) and its methyl and n-propyl substituted derivatives, are described. The complexes dichlorobis(1-methylimidazolidine-2- thione-S)-zinc(II) (1) and dichlorobis(1-propylimidazolidine-2-thione-S)- zinc(II) (2) have been characterized by single-crystal X-ray methods. Both complexes adopt distorted tetrahedral geometry. Only intramolecular hydrogen bonding interactions are observed in 1 and 2. Solution and solid state 13C NMR show a significant shift of the C=S carbon resonance of the ligands, while other resonances are relatively unaffected, indicating that most likely the solid state structure is maintained in solution. Antimicrobial activity studies of the free ligands and their complexes show that ligands exhibit substantial antibacterial activities compared to the complexes.

AB - The preparation and characterization of zinc complexes of formula ZnL2X2 (X = Cl and Br), with L = 1,3-diazinane-2-thione (Diaz), 1,3-diazipane-2-thione (Diap), imidazolidine-2-thione (Imt) and its methyl and n-propyl substituted derivatives, are described. The complexes dichlorobis(1-methylimidazolidine-2- thione-S)-zinc(II) (1) and dichlorobis(1-propylimidazolidine-2-thione-S)- zinc(II) (2) have been characterized by single-crystal X-ray methods. Both complexes adopt distorted tetrahedral geometry. Only intramolecular hydrogen bonding interactions are observed in 1 and 2. Solution and solid state 13C NMR show a significant shift of the C=S carbon resonance of the ligands, while other resonances are relatively unaffected, indicating that most likely the solid state structure is maintained in solution. Antimicrobial activity studies of the free ligands and their complexes show that ligands exhibit substantial antibacterial activities compared to the complexes.

KW - Antibacterial activity

KW - Crystal structure

KW - Imidazolidine-2-thione

KW - MAS NMR

KW - Zinc

UR - https://www.scopus.com/pages/publications/33947389602

U2 - 10.1080/00958970600780965

DO - 10.1080/00958970600780965

M3 - Article

AN - SCOPUS:33947389602

SN - 0095-8972

VL - 60

SP - 369

EP - 377

JO - Journal of Coordination Chemistry

JF - Journal of Coordination Chemistry

IS - 4

ER -

Zinc halide complexes of imidazolidine-2-thione and its derivatives: X-ray structures, solid state, solution NMR and antimicrobial activity studies

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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