Abstract
To gel well: The asymmetric reduction of hydrophobic ketones by xerogel-immobilized W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus (TeSADH) in organic solvents affords their S-configured alcohols in yields comparable with those achieved by using the free enzyme, and, in some cases, with higher enantioselectivities. R = phenyl-ring-containing substituent. (Figure Presented).
| Original language | English |
|---|---|
| Pages (from-to) | 3091-3094 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 46 |
| Issue number | 17 |
| DOIs | |
| State | Published - 2007 |
| Externally published | Yes |
Keywords
- Asymmetric catalysis
- Enantioselectivity
- Enzymes
- Oxidoreductases
- Sol-gel processes
ASJC Scopus subject areas
- Catalysis
- General Chemistry