Abstract
The human microbiota plays a crucial role in maintaining overall health and well-being. The gut microbiota has been implicated in developing and progressing various diseases, including cancer. This review highlights the related mechanisms and the compositions that influence cancer pathogenesis with a highlight on gastric cancer. We provide a comprehensive overview of the mechanisms by which the microbiome influences cancer development, progression, and response to treatment, with a focus on identifying potential biomarkers for early detection, prevention strategies, and novel therapeutic interventions that leverage microbiome modulation. This comprehensive review can guide future research and clinical practices in understanding and harnessing the microbiome to optimize gastric cancer therapies.
| Original language | English |
|---|---|
| Article number | 226 |
| Journal | Cancers |
| Volume | 17 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 2025 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2025 by the authors.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- chemotherapy
- gastric cancer
- immune checkpoint blockade
- microbiome
- microbiome modulation
ASJC Scopus subject areas
- Oncology
- Cancer Research
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