Abstract
The first total synthesis of aspergillusol A, an α-glucosidase inhibitor, was accomplished in an overall high yielding reaction sequence. A convergent synthetic approach was adopted; the erythritol segment of the molecule was derived from L-arabinose, whereas hydroxyphenylpyruvic acid oxime was built up from 4-hydroxybenzaldehyde.
| Original language | English |
|---|---|
| Pages (from-to) | 1077-1080 |
| Number of pages | 4 |
| Journal | Natural Product Communications |
| Volume | 5 |
| Issue number | 7 |
| DOIs | |
| State | Published - 2010 |
Keywords
- Antihyperglycemic drug
- Aspergillusol A
- Total synthesis
- α-glucosidase inhibitor
ASJC Scopus subject areas
- Pharmacology
- Plant Science
- Drug Discovery
- Complementary and alternative medicine
Fingerprint
Dive into the research topics of 'The first total synthesis of aspergillusol A, an α-glucosidase inhibitor'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver