The first N-heterocyclic carbene-based nickel catalyst for C-S coupling

Zhang Yugen; Chin Ngeow Kao; Jackie Y. Ying

doi:10.1021/ol071248x

The first N-heterocyclic carbene-based nickel catalyst for C-S coupling

Zhang Yugen^*, Chin Ngeow Kao, Jackie Y. Ying

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

358 Scopus citations

Abstract

We have developed the first N-heterocyclic carbene (NHC)-based transition metal catalysts for C-S coupling reactions. Ni-NHC catalysts showed good to excellent activities toward various aryl halides in C-S coupling reactions. The catalytic activities were greatly affected by the electronic and steric properties of the NHC ligands. The new catalysts were inexpensive, easy to synthesize, and environmentally friendly. They could be excellent candidates to replace Pd-organophosphanes for C-S coupling catalysis.

Original language	English
Pages (from-to)	3495-3498
Number of pages	4
Journal	Organic Letters
Volume	9
Issue number	18
DOIs	https://doi.org/10.1021/ol071248x
State	Published - 30 Aug 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol071248x

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title = "The first N-heterocyclic carbene-based nickel catalyst for C-S coupling",

abstract = "We have developed the first N-heterocyclic carbene (NHC)-based transition metal catalysts for C-S coupling reactions. Ni-NHC catalysts showed good to excellent activities toward various aryl halides in C-S coupling reactions. The catalytic activities were greatly affected by the electronic and steric properties of the NHC ligands. The new catalysts were inexpensive, easy to synthesize, and environmentally friendly. They could be excellent candidates to replace Pd-organophosphanes for C-S coupling catalysis.",

author = "Zhang Yugen and Kao, \{Chin Ngeow\} and Ying, \{Jackie Y.\}",

year = "2007",

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doi = "10.1021/ol071248x",

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journal = "Organic Letters",

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AU - Yugen, Zhang

AU - Kao, Chin Ngeow

AU - Ying, Jackie Y.

PY - 2007/8/30

Y1 - 2007/8/30

N2 - We have developed the first N-heterocyclic carbene (NHC)-based transition metal catalysts for C-S coupling reactions. Ni-NHC catalysts showed good to excellent activities toward various aryl halides in C-S coupling reactions. The catalytic activities were greatly affected by the electronic and steric properties of the NHC ligands. The new catalysts were inexpensive, easy to synthesize, and environmentally friendly. They could be excellent candidates to replace Pd-organophosphanes for C-S coupling catalysis.

AB - We have developed the first N-heterocyclic carbene (NHC)-based transition metal catalysts for C-S coupling reactions. Ni-NHC catalysts showed good to excellent activities toward various aryl halides in C-S coupling reactions. The catalytic activities were greatly affected by the electronic and steric properties of the NHC ligands. The new catalysts were inexpensive, easy to synthesize, and environmentally friendly. They could be excellent candidates to replace Pd-organophosphanes for C-S coupling catalysis.

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U2 - 10.1021/ol071248x

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M3 - Article

C2 - 17676857

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JO - Organic Letters

JF - Organic Letters

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ER -

The first N-heterocyclic carbene-based nickel catalyst for C-S coupling

Abstract

ASJC Scopus subject areas

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