The conformational analysis of 3-hydroxytetrahydro-1,3-oxazines by NMR spectroscopy

Sk Asrof Ali; Syed M.A. Hashmi; Mohammed I.M. Wazeer

doi:10.1016/S1386-1425(98)00319-9

The conformational analysis of 3-hydroxytetrahydro-1,3-oxazines by NMR spectroscopy

Sk Asrof Ali^*
, Syed M.A. Hashmi
, Mohammed I.M. Wazeer

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The stereochemistry of the preferred conformers of several 3-hydroxytetrahydro-1,3-oxazines has been established by NMR spectroscopy. Strong anomeric effect stabilises the conformation having equatorial orientation of the lone pair on nitrogen. Nitrogen inversion process was found to be the rate limiting process in the conformational equilibria.

Original language	English
Pages (from-to)	1445-1452
Number of pages	8
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	55
Issue number	7-8
DOIs	https://doi.org/10.1016/S1386-1425(98)00319-9
State	Published - 1999

Keywords

Anomeric effect
NMR spectroscopy
Nitrogen inversion

ASJC Scopus subject areas

Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Spectroscopy

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10.1016/S1386-1425(98)00319-9

Cite this

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title = "The conformational analysis of 3-hydroxytetrahydro-1,3-oxazines by NMR spectroscopy",

abstract = "The stereochemistry of the preferred conformers of several 3-hydroxytetrahydro-1,3-oxazines has been established by NMR spectroscopy. Strong anomeric effect stabilises the conformation having equatorial orientation of the lone pair on nitrogen. Nitrogen inversion process was found to be the rate limiting process in the conformational equilibria.",

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T1 - The conformational analysis of 3-hydroxytetrahydro-1,3-oxazines by NMR spectroscopy

AU - Ali, Sk Asrof

AU - Hashmi, Syed M.A.

AU - Wazeer, Mohammed I.M.

PY - 1999

Y1 - 1999

N2 - The stereochemistry of the preferred conformers of several 3-hydroxytetrahydro-1,3-oxazines has been established by NMR spectroscopy. Strong anomeric effect stabilises the conformation having equatorial orientation of the lone pair on nitrogen. Nitrogen inversion process was found to be the rate limiting process in the conformational equilibria.

AB - The stereochemistry of the preferred conformers of several 3-hydroxytetrahydro-1,3-oxazines has been established by NMR spectroscopy. Strong anomeric effect stabilises the conformation having equatorial orientation of the lone pair on nitrogen. Nitrogen inversion process was found to be the rate limiting process in the conformational equilibria.

KW - Anomeric effect

KW - NMR spectroscopy

KW - Nitrogen inversion

UR - https://www.scopus.com/pages/publications/2042480477

U2 - 10.1016/S1386-1425(98)00319-9

DO - 10.1016/S1386-1425(98)00319-9

M3 - Article

AN - SCOPUS:2042480477

SN - 1386-1425

VL - 55

SP - 1445

EP - 1452

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

IS - 7-8

ER -

The conformational analysis of 3-hydroxytetrahydro-1,3-oxazines by NMR spectroscopy

Abstract

Keywords

ASJC Scopus subject areas

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