Synthesis of unsaturated acids by 1,2-addition of formic acid to conjugated dienes catalyzed by palladium on carbon in the presence of mono and bidentate phosphines

Giuseppe Vasapollo; Anoma Somasunderam; Bassam El Ali; Howard Alper

doi:10.1016/S0040-4039(00)73391-0

Synthesis of unsaturated acids by 1,2-addition of formic acid to conjugated dienes catalyzed by palladium on carbon in the presence of mono and bidentate phosphines

Giuseppe Vasapollo^*
, Anoma Somasunderam
, Bassam El Ali
, Howard Alper

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Di-, and trisubstituted 1,3-dienes are converted to γ,δ-unsaturated acids by use of formic acid, carbon monoxide, and catalytic quantities of PdC / PPh₃ / Ph₂P(CH₂)₄PPh₂ in 1,2-dimethoxyethane. A β,γ-unsaturated acid was obtained when the monosubstituted diene, isoprene, was used as the reactant.

Original language	English
Pages (from-to)	6203-6206
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	34
DOIs	https://doi.org/10.1016/S0040-4039(00)73391-0
State	Published - 22 Aug 1994
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/S0040-4039(00)73391-0

Cite this

@article{cc9731214d58467eb6578da45f7413f7,

title = "Synthesis of unsaturated acids by 1,2-addition of formic acid to conjugated dienes catalyzed by palladium on carbon in the presence of mono and bidentate phosphines",

abstract = "Di-, and trisubstituted 1,3-dienes are converted to γ,δ-unsaturated acids by use of formic acid, carbon monoxide, and catalytic quantities of PdC / PPh3 / Ph2P(CH2)4PPh2 in 1,2-dimethoxyethane. A β,γ-unsaturated acid was obtained when the monosubstituted diene, isoprene, was used as the reactant.",

author = "Giuseppe Vasapollo and Anoma Somasunderam and \{El Ali\}, Bassam and Howard Alper",

year = "1994",

month = aug,

day = "22",

doi = "10.1016/S0040-4039(00)73391-0",

language = "English",

volume = "35",

pages = "6203--6206",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "34",

}

TY - JOUR

T1 - Synthesis of unsaturated acids by 1,2-addition of formic acid to conjugated dienes catalyzed by palladium on carbon in the presence of mono and bidentate phosphines

AU - Vasapollo, Giuseppe

AU - Somasunderam, Anoma

AU - El Ali, Bassam

AU - Alper, Howard

PY - 1994/8/22

Y1 - 1994/8/22

N2 - Di-, and trisubstituted 1,3-dienes are converted to γ,δ-unsaturated acids by use of formic acid, carbon monoxide, and catalytic quantities of PdC / PPh3 / Ph2P(CH2)4PPh2 in 1,2-dimethoxyethane. A β,γ-unsaturated acid was obtained when the monosubstituted diene, isoprene, was used as the reactant.

AB - Di-, and trisubstituted 1,3-dienes are converted to γ,δ-unsaturated acids by use of formic acid, carbon monoxide, and catalytic quantities of PdC / PPh3 / Ph2P(CH2)4PPh2 in 1,2-dimethoxyethane. A β,γ-unsaturated acid was obtained when the monosubstituted diene, isoprene, was used as the reactant.

UR - https://www.scopus.com/pages/publications/0027993718

U2 - 10.1016/S0040-4039(00)73391-0

DO - 10.1016/S0040-4039(00)73391-0

M3 - Article

AN - SCOPUS:0027993718

SN - 0040-4039

VL - 35

SP - 6203

EP - 6206

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 34

ER -

Synthesis of unsaturated acids by 1,2-addition of formic acid to conjugated dienes catalyzed by palladium on carbon in the presence of mono and bidentate phosphines

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this