Synthesis of Chiral sec-Alcohols by Ketone Reduction

David Pollard; Matthew Truppo; Jeffrey Moore; Birgit Kosjek; David Tellers; Jeffrey Moore; Ioulia Smonou; Dimitris Kalaitzakis; Musa M. Musa; Karla I. Ziegelmann-Fjeld; Claire Vieille; J. Gregory Zeikus; Robert S. Phillipsa; Matthew Truppo; Krista Morley; Paul Devine; Tadashi Ema; Nobuyasu Okita; Sayaka Ide; Takashi Sakai

doi:10.1002/9780470748589.ch8

Synthesis of Chiral sec-Alcohols by Ketone Reduction

David Pollard^*, Matthew Truppo, Jeffrey Moore, Birgit Kosjek, David Tellers, Jeffrey Moore, Ioulia Smonou, Dimitris Kalaitzakis, Musa M. Musa, Karla I. Ziegelmann-Fjeld, Claire Vieille, J. Gregory Zeikus, Robert S. Phillipsa, Matthew Truppo, Krista Morley, Paul Devine, Tadashi Ema, Nobuyasu Okita, Sayaka Ide, Takashi Sakai

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Original language	English
Title of host publication	Practical Methods for Biocatalysis and Biotransformations
Publisher	John Wiley & Sons, Ltd
Pages	273-275
Number of pages	3
ISBN (Print)	9780470519271
DOIs	https://doi.org/10.1002/9780470748589.ch8
State	Published - 15 Dec 2009
Externally published	Yes

Keywords

Alcohol dehydrogenase ADH-RE
Asymmetric synthesis of (S)-Bis(trifluoromethyl)phenylethanol
Enantioselective and diastereoselective enzyme-catalyzed dynamic kinetic resolution of unsaturated ketone
Enzyme-catalysed stereoselective reduction of diketones/keto esters to keto alcohols/hydroxy esters
Ketoreductase reduction of diaryl ketones
Ketoreductase reduction of ketone 1
Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs)
Screening of ketoreductase enzymes
Synthesis of chiral sec-alcohols by ketone reduction
Thermoanaerobacter ethanolicus (W110A TeSADH)

ASJC Scopus subject areas

General Chemical Engineering

Access to Document

10.1002/9780470748589.ch8

Cite this

Pollard, D., Truppo, M., Moore, J., Kosjek, B., Tellers, D., Moore, J., Smonou, I., Kalaitzakis, D., Musa, M. M., Ziegelmann-Fjeld, K. I., Vieille, C., Zeikus, J. G., Phillipsa, R. S., Truppo, M., Morley, K., Devine, P., Ema, T., Okita, N., Ide, S., & Sakai, T. (2009). Synthesis of Chiral sec-Alcohols by Ketone Reduction. In Practical Methods for Biocatalysis and Biotransformations (pp. 273-275). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470748589.ch8

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title = "Synthesis of Chiral sec-Alcohols by Ketone Reduction",

keywords = "Alcohol dehydrogenase ADH-RE, Asymmetric synthesis of (S)-Bis(trifluoromethyl)phenylethanol, Enantioselective and diastereoselective enzyme-catalyzed dynamic kinetic resolution of unsaturated ketone, Enzyme-catalysed stereoselective reduction of diketones/keto esters to keto alcohols/hydroxy esters, Ketoreductase reduction of diaryl ketones, Ketoreductase reduction of ketone 1, Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs), Screening of ketoreductase enzymes, Synthesis of chiral sec-alcohols by ketone reduction, Thermoanaerobacter ethanolicus (W110A TeSADH)",

author = "David Pollard and Matthew Truppo and Jeffrey Moore and Birgit Kosjek and David Tellers and Jeffrey Moore and Ioulia Smonou and Dimitris Kalaitzakis and Musa, \{Musa M.\} and Ziegelmann-Fjeld, \{Karla I.\} and Claire Vieille and Zeikus, \{J. Gregory\} and Phillipsa, \{Robert S.\} and Matthew Truppo and Krista Morley and Paul Devine and Tadashi Ema and Nobuyasu Okita and Sayaka Ide and Takashi Sakai",

year = "2009",

month = dec,

day = "15",

doi = "10.1002/9780470748589.ch8",

language = "English",

isbn = "9780470519271",

pages = "273--275",

booktitle = "Practical Methods for Biocatalysis and Biotransformations",

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Pollard, D, Truppo, M, Moore, J, Kosjek, B, Tellers, D, Moore, J, Smonou, I, Kalaitzakis, D, Musa, MM, Ziegelmann-Fjeld, KI, Vieille, C, Zeikus, JG, Phillipsa, RS, Truppo, M, Morley, K, Devine, P, Ema, T, Okita, N, Ide, S & Sakai, T 2009, Synthesis of Chiral sec-Alcohols by Ketone Reduction. in Practical Methods for Biocatalysis and Biotransformations. John Wiley & Sons, Ltd, pp. 273-275. https://doi.org/10.1002/9780470748589.ch8

TY - CHAP

T1 - Synthesis of Chiral sec-Alcohols by Ketone Reduction

AU - Pollard, David

AU - Truppo, Matthew

AU - Moore, Jeffrey

AU - Kosjek, Birgit

AU - Tellers, David

AU - Moore, Jeffrey

AU - Smonou, Ioulia

AU - Kalaitzakis, Dimitris

AU - Musa, Musa M.

AU - Ziegelmann-Fjeld, Karla I.

AU - Vieille, Claire

AU - Zeikus, J. Gregory

AU - Phillipsa, Robert S.

AU - Truppo, Matthew

AU - Morley, Krista

AU - Devine, Paul

AU - Ema, Tadashi

AU - Okita, Nobuyasu

AU - Ide, Sayaka

AU - Sakai, Takashi

PY - 2009/12/15

Y1 - 2009/12/15

KW - Alcohol dehydrogenase ADH-RE

KW - Asymmetric synthesis of (S)-Bis(trifluoromethyl)phenylethanol

KW - Enantioselective and diastereoselective enzyme-catalyzed dynamic kinetic resolution of unsaturated ketone

KW - Enzyme-catalysed stereoselective reduction of diketones/keto esters to keto alcohols/hydroxy esters

KW - Ketoreductase reduction of diaryl ketones

KW - Ketoreductase reduction of ketone 1

KW - Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs)

KW - Screening of ketoreductase enzymes

KW - Synthesis of chiral sec-alcohols by ketone reduction

KW - Thermoanaerobacter ethanolicus (W110A TeSADH)

UR - https://www.scopus.com/pages/publications/84889303034

U2 - 10.1002/9780470748589.ch8

DO - 10.1002/9780470748589.ch8

M3 - Chapter

AN - SCOPUS:84889303034

SN - 9780470519271

SP - 273

EP - 275

BT - Practical Methods for Biocatalysis and Biotransformations

PB - John Wiley & Sons, Ltd

ER -