Synthesis, Hirshfeld surface analysis, computational, wave function properties, anticancer and cytotoxicity activity of di[(p-chlorobenzyl) (dibromo)] (4,7-dimethyl-1,10-phenanthroline)tin (IV) complex

The complex di[(p-chlorobenzyl) (dibromo)] (4,7-dimethyl-1,10-phenanthroline)tin (IV) (SA1), were synthesized by reacting the 4,7-dimethyl-1,10-phenanthroline with the selected di[(p-chlorobenzyl) (dibromide) in methanol at the right mole ratio. The complex SA1, while environmental conditions in dry air, are quite stable in moist air and can be dissolved in a wide variety of organic solvents. Spectral, structural, theoretical, and biological analyses all looked into the products, and they all strongly supported up the expected molecular structures for complex formation. The compound molecular structure and geometry were defined using DFT and X-ray analysis. Topological studies, like ELF, LOL, ALIE, and RDG studies, were done with the Multiwfn-3.8 to find the main binding areas and weak interactions in the molecule. The HOMO-LUMO, MEP, and NLO properties were carried out in the gas phase. The complex SA1 study the anticancer and cytotoxicity activity using the HeLa and Vera cell lines. On the HeLa cell lines, the experiment findings demonstrated that the complex SA1 exhibited a higher level of activity than the standard treatment, cisplatin.