Synthesis, CP-MAS NMR characterization, and antibacterial activities of glycine and histidine complexes of Cd(SeCN)²and Hg(SeCN)²

The synthesis and characterization of cadmium and mercury complexes of selenocyanate of the type [(L)M(SeCN)²] are described, where L is L-Histidine (His) or L-Glycine (Gly) and M is Cd²⁺ or Hg ²⁺. These complexes are obtained by the reaction of 1 equivalent of respective amino acids with metal diselenocyanate precursor in a mixture of solvents (methanol: water = 1: 1). These synthesized compounds are characterized by analytical and various spectroscopic techniques such as elemental analysis (EA), IR, H, 1 and C 13 NMR in solution and in the solid state for C 13 and N 15. The in vitro antibacterial activities of these complexes have been investigated with standard type cultures of Escherichia coli (MTCC 443), Klebsiella pneumoniae (MTCC 109), Pseudomonas aeruginosa (MTCC 1688), Salmonella typhi (MTCC 733), and Staphylococcus aureus (MTCC 737).