TY - JOUR
T1 - Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase. the crystal structure of trans-dichloro-(m-chloroaniline) (triphenylphosphine)palladium(II)
AU - Asma, Maliha
AU - Badshah, Amin
AU - Ali, Saqib
AU - Sohail, Manzar
AU - Fettouhi, Mohammed
AU - Ahmad, Saeed
AU - Malik, Abdul
PY - 2006/5
Y1 - 2006/5
N2 - A number of palladium(II) complexes with Ph3P and aromatic amines as ligands having the general formula [(Ph3P)Pd(Ph 3P)(NH2R)Cl2] {where R = Ph (1), m-ClC 6H4 (2), p-ClC6H5 (3)} and [Pd(CH3NHPh)Cl2] (4), have been synthesized and characterized by elemental analysis, IR, 1H and 13C NMR. The X-ray crystal structure of [(Ph3P)Pd(m-ClC6H 4NH2)Cl2] · CH2 Cl 2 (2) shows a distorted square planar environment around the Pd(II) ion with the P-Pd-N and Cl(1)-Pd-Cl(2) bond angles of 174.88(5)° and 176.77(2)° respectively. The complexes were screened for enzyme inhibition activity against β-glucuronidase and found to be active.
AB - A number of palladium(II) complexes with Ph3P and aromatic amines as ligands having the general formula [(Ph3P)Pd(Ph 3P)(NH2R)Cl2] {where R = Ph (1), m-ClC 6H4 (2), p-ClC6H5 (3)} and [Pd(CH3NHPh)Cl2] (4), have been synthesized and characterized by elemental analysis, IR, 1H and 13C NMR. The X-ray crystal structure of [(Ph3P)Pd(m-ClC6H 4NH2)Cl2] · CH2 Cl 2 (2) shows a distorted square planar environment around the Pd(II) ion with the P-Pd-N and Cl(1)-Pd-Cl(2) bond angles of 174.88(5)° and 176.77(2)° respectively. The complexes were screened for enzyme inhibition activity against β-glucuronidase and found to be active.
UR - https://www.scopus.com/pages/publications/33646727352
U2 - 10.1007/s11243-006-0027-z
DO - 10.1007/s11243-006-0027-z
M3 - Article
AN - SCOPUS:33646727352
SN - 0340-4285
VL - 31
SP - 556
EP - 559
JO - Transition Metal Chemistry
JF - Transition Metal Chemistry
IS - 4
ER -