Synthesis, characterization, and in vitro antimicrobial studies of heteroleptic silver(I) polymers

Asima Munawar; Helen Stoeckli-Evans; Anvarhussein A. Isab; Imran Rashid; Raja Shahid Ashraf; Muhammad Altaf

doi:10.1016/j.poly.2023.116447

Synthesis, characterization, and in vitro antimicrobial studies of heteroleptic silver(I) polymers

Asima Munawar
, Helen Stoeckli-Evans
, Anvarhussein A. Isab
, Imran Rashid
, Raja Shahid Ashraf
, Muhammad Altaf^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Three new heteroleptic silver(I) polymers (1–3) with tricyclohexyl phosphine and pyridine derivatives such as [Ag₂(L1)(TCHP)₂(NO₃)₂]_n (1), [Ag₂(L2)(TCHP)₂(NO₃)₂]_n (2) and [Ag₂(L3)(TCHP)₂(NO₃)₂]_n (3) were synthesized and characterized by elemental analysis, ¹H, ¹³C{¹H} and ³¹P{¹H} NMR spectroscopy. The structure of polymers 1 and 2 were solved by using single-crystal X-ray diffraction analysis. Antimicrobial studies of the synthesized polymers (1–3) were done by evaluating their minimum inhibitory concentrations (MIC). All polymers exhibited good potential against gram-negative strains such as Escherichia coli and Pseudomonas aeruginosa and gram-positive strains such as Bacillus subtillis and Staphylococcus aureus, MIC values mutable 0.125–0.0312 mg/ml. All synthesized polymers were also tested against Fusarium oxysporum, Rhizopus oligosporus and trichophyton rubrum for their antifungal potential and MIC values ranges from 0.125−0.0625 mg/ml.

Original language	English
Article number	116447
Journal	Polyhedron
Volume	240
DOIs	https://doi.org/10.1016/j.poly.2023.116447
State	Published - 1 Aug 2023

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Ltd

Keywords

Antibacterial
Antifungal
Heteroleptic
Silver
X-ray diffraction

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry
Materials Chemistry

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10.1016/j.poly.2023.116447

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title = "Synthesis, characterization, and in vitro antimicrobial studies of heteroleptic silver(I) polymers",

abstract = "Three new heteroleptic silver(I) polymers (1–3) with tricyclohexyl phosphine and pyridine derivatives such as [Ag2(L1)(TCHP)2(NO3)2]n (1), [Ag2(L2)(TCHP)2(NO3)2]n (2) and [Ag2(L3)(TCHP)2(NO3)2]n (3) were synthesized and characterized by elemental analysis, 1H, 13C\{1H\} and 31P\{1H\} NMR spectroscopy. The structure of polymers 1 and 2 were solved by using single-crystal X-ray diffraction analysis. Antimicrobial studies of the synthesized polymers (1–3) were done by evaluating their minimum inhibitory concentrations (MIC). All polymers exhibited good potential against gram-negative strains such as Escherichia coli and Pseudomonas aeruginosa and gram-positive strains such as Bacillus subtillis and Staphylococcus aureus, MIC values mutable 0.125–0.0312 mg/ml. All synthesized polymers were also tested against Fusarium oxysporum, Rhizopus oligosporus and trichophyton rubrum for their antifungal potential and MIC values ranges from 0.125−0.0625 mg/ml.",

keywords = "Antibacterial, Antifungal, Heteroleptic, Silver, X-ray diffraction",

author = "Asima Munawar and Helen Stoeckli-Evans and Isab, \{Anvarhussein A.\} and Imran Rashid and Ashraf, \{Raja Shahid\} and Muhammad Altaf",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Ltd",

year = "2023",

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doi = "10.1016/j.poly.2023.116447",

language = "English",

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TY - JOUR

T1 - Synthesis, characterization, and in vitro antimicrobial studies of heteroleptic silver(I) polymers

AU - Munawar, Asima

AU - Stoeckli-Evans, Helen

AU - Isab, Anvarhussein A.

AU - Rashid, Imran

AU - Ashraf, Raja Shahid

AU - Altaf, Muhammad

PY - 2023/8/1

Y1 - 2023/8/1

N2 - Three new heteroleptic silver(I) polymers (1–3) with tricyclohexyl phosphine and pyridine derivatives such as [Ag2(L1)(TCHP)2(NO3)2]n (1), [Ag2(L2)(TCHP)2(NO3)2]n (2) and [Ag2(L3)(TCHP)2(NO3)2]n (3) were synthesized and characterized by elemental analysis, 1H, 13C{1H} and 31P{1H} NMR spectroscopy. The structure of polymers 1 and 2 were solved by using single-crystal X-ray diffraction analysis. Antimicrobial studies of the synthesized polymers (1–3) were done by evaluating their minimum inhibitory concentrations (MIC). All polymers exhibited good potential against gram-negative strains such as Escherichia coli and Pseudomonas aeruginosa and gram-positive strains such as Bacillus subtillis and Staphylococcus aureus, MIC values mutable 0.125–0.0312 mg/ml. All synthesized polymers were also tested against Fusarium oxysporum, Rhizopus oligosporus and trichophyton rubrum for their antifungal potential and MIC values ranges from 0.125−0.0625 mg/ml.

AB - Three new heteroleptic silver(I) polymers (1–3) with tricyclohexyl phosphine and pyridine derivatives such as [Ag2(L1)(TCHP)2(NO3)2]n (1), [Ag2(L2)(TCHP)2(NO3)2]n (2) and [Ag2(L3)(TCHP)2(NO3)2]n (3) were synthesized and characterized by elemental analysis, 1H, 13C{1H} and 31P{1H} NMR spectroscopy. The structure of polymers 1 and 2 were solved by using single-crystal X-ray diffraction analysis. Antimicrobial studies of the synthesized polymers (1–3) were done by evaluating their minimum inhibitory concentrations (MIC). All polymers exhibited good potential against gram-negative strains such as Escherichia coli and Pseudomonas aeruginosa and gram-positive strains such as Bacillus subtillis and Staphylococcus aureus, MIC values mutable 0.125–0.0312 mg/ml. All synthesized polymers were also tested against Fusarium oxysporum, Rhizopus oligosporus and trichophyton rubrum for their antifungal potential and MIC values ranges from 0.125−0.0625 mg/ml.

KW - Antibacterial

KW - Antifungal

KW - Heteroleptic

KW - Silver

KW - X-ray diffraction

UR - https://www.scopus.com/pages/publications/85159283836

U2 - 10.1016/j.poly.2023.116447

DO - 10.1016/j.poly.2023.116447

M3 - Article

AN - SCOPUS:85159283836

SN - 0277-5387

VL - 240

JO - Polyhedron

JF - Polyhedron

M1 - 116447

ER -

Synthesis, characterization, and in vitro antimicrobial studies of heteroleptic silver(I) polymers

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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