TY - JOUR
T1 - Synthesis, characterization and antimicrobial studies of mixed ligand silver(I) complexes of thioureas and triphenylphosphine; crystal structure of {[Ag(PPh3)(thiourea)(NO3)]2·[Ag( PPh3)(thiourea)]2(NO3)2}
AU - Isab, Anvarhusein A.
AU - Nawaz, Sidra
AU - Saleem, Muhammad
AU - Altaf, Muhammad
AU - Monim-ul-Mehboob, Muhammad
AU - Ahmad, Saeed
AU - Evans, Helen Stoeckli
PY - 2010/3/10
Y1 - 2010/3/10
N2 - Mixed ligand silver(I) complexes of triphenylphosphine and thioureas (thiourea (Tu), N-methylthiourea (Metu), N,N′-dimethylthiourea (Dmtu) and N,N′-diethylthiourea (Detu)) with the general formulae, [(Ph3P)2Ag(thione)]NO3 and [(Ph3P)Ag(thione)2]NO3, have been prepared and characterized by elemental analysis, IR and NMR (1H, 13C and 31P) spectroscopic methods. The crystal structure of one of them has been determined by X-ray crystallography. The spectral data of the complexes are consistent with sulfur coordination of the thiones to silver(I). The single crystal X-ray structure of complex 1, {[Ag(PPh3)(thiourea)(NO3)]2·[Ag( PPh3)(thiourea)]2(NO3)2}, shows that the complex consists of two independent centrosymmetric binuclear units, each having the silver atoms coordinated to one PPh3 and two bridging thiourea molecules. In one of the independent units the silver atom is additionally bound to a nitrate ion, leading to a tetrahedral geometry, while in the other unit the silver atom adopts a trigonal planar environment. Antimicrobial activities of the complexes were evaluated by their minimum inhibitory concentration and the results showed that the complexes show a wide range of activity against two gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and molds (Aspergillus niger, Penicillium citrinum), while the activities were poor against yeasts (Candida albicans, Saccharomyces cerevisiae). However, the title complex did not show activity against any tested microorganism.
AB - Mixed ligand silver(I) complexes of triphenylphosphine and thioureas (thiourea (Tu), N-methylthiourea (Metu), N,N′-dimethylthiourea (Dmtu) and N,N′-diethylthiourea (Detu)) with the general formulae, [(Ph3P)2Ag(thione)]NO3 and [(Ph3P)Ag(thione)2]NO3, have been prepared and characterized by elemental analysis, IR and NMR (1H, 13C and 31P) spectroscopic methods. The crystal structure of one of them has been determined by X-ray crystallography. The spectral data of the complexes are consistent with sulfur coordination of the thiones to silver(I). The single crystal X-ray structure of complex 1, {[Ag(PPh3)(thiourea)(NO3)]2·[Ag( PPh3)(thiourea)]2(NO3)2}, shows that the complex consists of two independent centrosymmetric binuclear units, each having the silver atoms coordinated to one PPh3 and two bridging thiourea molecules. In one of the independent units the silver atom is additionally bound to a nitrate ion, leading to a tetrahedral geometry, while in the other unit the silver atom adopts a trigonal planar environment. Antimicrobial activities of the complexes were evaluated by their minimum inhibitory concentration and the results showed that the complexes show a wide range of activity against two gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and molds (Aspergillus niger, Penicillium citrinum), while the activities were poor against yeasts (Candida albicans, Saccharomyces cerevisiae). However, the title complex did not show activity against any tested microorganism.
KW - Antimicrobial activity
KW - Crystal structure
KW - Silver(I) complexes
KW - Spectroscopy
KW - Thiourea
KW - Triphenylphosphine
UR - https://www.scopus.com/pages/publications/77049094396
U2 - 10.1016/j.poly.2009.12.037
DO - 10.1016/j.poly.2009.12.037
M3 - Article
AN - SCOPUS:77049094396
SN - 0277-5387
VL - 29
SP - 1251
EP - 1256
JO - Polyhedron
JF - Polyhedron
IS - 4
ER -