TY - JOUR
T1 - Synthesis, characterization and antimicrobial studies of mixed ligand silver(I) complexes of triphenylphosphine and heterocyclic thiones
T2 - Crystal structure of bis[{(μ2-diazinane-2-thione)(diazinane-2-thione) (triphenylphosphine)silver(I) nitrate}]
AU - Nawaz, Sidra
AU - Isab, Anvarhusein A.
AU - Merz, Klaus
AU - Vasylyeva, Vera
AU - Metzler-Nolte, Nils
AU - Saleem, Muhammad
AU - Ahmad, Saeed
PY - 2011/5/26
Y1 - 2011/5/26
N2 - Mixed ligand silver(I) complexes of triphenylphosphine and heterocyclic thiones (imidazolidine-2-thione (Imt), diazinane-2-thione (Diaz) and 2-mercaptopyridine (Mpy)) having the general formulae [(Ph3P) Ag(thione)2]NO3 and [(Ph3P) 2Ag(thione)]NO3 were prepared and characterized by elemental analysis, IR and NMR (1H, 13C and 31P) spectroscopic methods. The crystal structure of one of the complexes, [Ag(Ph3P)(Diaz)2]2(NO 3)2 (1) was determined by X-ray crystallography. The title complex (1) is dinuclear, having each silver atom coordinated to three thione sulfur atoms of Diaz and to one phosphorus atom of PPh3 in a nearly tetrahedral environment, with an average P-Ag-S bond angle of 108.5°. The spectral data of the complexes are consistent with sulfur coordination of the thiones to silver(I). Antimicrobial activities of the complexes were evaluated by minimum inhibitory concentrations and the results showed that the complexes exhibit a wide range of activity against two gram-negative bacteria (E. coli, P. aeruginosa) and molds (A. niger, P. citrinum), while the activities were poor against yeasts (C. albicans, S. cerevisiae).
AB - Mixed ligand silver(I) complexes of triphenylphosphine and heterocyclic thiones (imidazolidine-2-thione (Imt), diazinane-2-thione (Diaz) and 2-mercaptopyridine (Mpy)) having the general formulae [(Ph3P) Ag(thione)2]NO3 and [(Ph3P) 2Ag(thione)]NO3 were prepared and characterized by elemental analysis, IR and NMR (1H, 13C and 31P) spectroscopic methods. The crystal structure of one of the complexes, [Ag(Ph3P)(Diaz)2]2(NO 3)2 (1) was determined by X-ray crystallography. The title complex (1) is dinuclear, having each silver atom coordinated to three thione sulfur atoms of Diaz and to one phosphorus atom of PPh3 in a nearly tetrahedral environment, with an average P-Ag-S bond angle of 108.5°. The spectral data of the complexes are consistent with sulfur coordination of the thiones to silver(I). Antimicrobial activities of the complexes were evaluated by minimum inhibitory concentrations and the results showed that the complexes exhibit a wide range of activity against two gram-negative bacteria (E. coli, P. aeruginosa) and molds (A. niger, P. citrinum), while the activities were poor against yeasts (C. albicans, S. cerevisiae).
KW - Antimicrobial activity
KW - Silver(I) complexes
KW - Thiones
KW - Triphenylphosphine
KW - X-ray structure
UR - https://www.scopus.com/pages/publications/79955751926
U2 - 10.1016/j.poly.2011.02.054
DO - 10.1016/j.poly.2011.02.054
M3 - Article
AN - SCOPUS:79955751926
SN - 0277-5387
VL - 30
SP - 1502
EP - 1506
JO - Polyhedron
JF - Polyhedron
IS - 9
ER -