15N NMR studies of the binding of C15N- with gold(I) drugs

Anvarhusein A. Isab; Ibrahim H. Ghazi; Mohammed I.M. Wazeer; Herman P. Perzanowski

doi:10.1016/0162-0134(93)80056-F

¹⁵N NMR studies of the binding of C¹⁵N^- with gold(I) drugs

Anvarhusein A. Isab^*, Ibrahim H. Ghazi, Mohammed I.M. Wazeer, Herman P. Perzanowski

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

¹⁵N NMR studies of the interaction of ¹⁵N cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two ¹⁵N ions containing species Au(C¹⁵N)₂^- and RS-Au-C¹⁵N^- (where RS^- = tm^- or tg^-) were identified at 265.94 and 260.30 ppm, respectively. From the broadened ¹⁵N NMR signals, approximate life times of the RS-Au-CN^- species were calculated.

Original language	English
Pages (from-to)	299-304
Number of pages	6
Journal	Journal of Inorganic Biochemistry
Volume	50
Issue number	4
DOIs	https://doi.org/10.1016/0162-0134(93)80056-F
State	Published - Jun 1993

ASJC Scopus subject areas

Biochemistry
Inorganic Chemistry

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10.1016/0162-0134(93)80056-F

Cite this

@article{9d2d669bbc9d4e16b6670f57c33e8dd6,

title = "15N NMR studies of the binding of C15N- with gold(I) drugs",

abstract = "15N NMR studies of the interaction of 15N cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two 15N ions containing species Au(C15N)2- and RS-Au-C15N- (where RS- = tm- or tg-) were identified at 265.94 and 260.30 ppm, respectively. From the broadened 15N NMR signals, approximate life times of the RS-Au-CN- species were calculated.",

author = "Isab, \{Anvarhusein A.\} and Ghazi, \{Ibrahim H.\} and Wazeer, \{Mohammed I.M.\} and Perzanowski, \{Herman P.\}",

year = "1993",

month = jun,

doi = "10.1016/0162-0134(93)80056-F",

language = "English",

volume = "50",

pages = "299--304",

journal = "Journal of Inorganic Biochemistry",

issn = "0162-0134",

number = "4",

}

TY - JOUR

T1 - 15N NMR studies of the binding of C15N- with gold(I) drugs

AU - Isab, Anvarhusein A.

AU - Ghazi, Ibrahim H.

AU - Wazeer, Mohammed I.M.

AU - Perzanowski, Herman P.

PY - 1993/6

Y1 - 1993/6

N2 - 15N NMR studies of the interaction of 15N cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two 15N ions containing species Au(C15N)2- and RS-Au-C15N- (where RS- = tm- or tg-) were identified at 265.94 and 260.30 ppm, respectively. From the broadened 15N NMR signals, approximate life times of the RS-Au-CN- species were calculated.

AB - 15N NMR studies of the interaction of 15N cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two 15N ions containing species Au(C15N)2- and RS-Au-C15N- (where RS- = tm- or tg-) were identified at 265.94 and 260.30 ppm, respectively. From the broadened 15N NMR signals, approximate life times of the RS-Au-CN- species were calculated.

UR - https://www.scopus.com/pages/publications/0027336540

U2 - 10.1016/0162-0134(93)80056-F

DO - 10.1016/0162-0134(93)80056-F

M3 - Article

C2 - 8331345

AN - SCOPUS:0027336540

SN - 0162-0134

VL - 50

SP - 299

EP - 304

JO - Journal of Inorganic Biochemistry

JF - Journal of Inorganic Biochemistry

IS - 4