Site-selective Sonogashira reactions of 1,2-dibromo-3,5-difluorobenzene

Sebastian Reimann; Peter Ehlers; Muhammad Sharif; Kai Wittler; Anke Spannenberg; Ralf Ludwig; Peter Langer

doi:10.1016/j.catcom.2012.03.022

Site-selective Sonogashira reactions of 1,2-dibromo-3,5-difluorobenzene

Sebastian Reimann
, Peter Ehlers
, Muhammad Sharif
, Kai Wittler
, Anke Spannenberg
, Ralf Ludwig
, Peter Langer^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A variety of mono- and diethynyl substituted fluorinated benzene derivatives was prepared by Sonogashira cross coupling reactions of 1,2-dibromo-3,5-difluorobenzene. The reactions proceed with very good site-selectivity in favor of position 1, due to electronic and steric reasons.

Original language	English
Pages (from-to)	142-147
Number of pages	6
Journal	Catalysis Communications
Volume	25
DOIs	https://doi.org/10.1016/j.catcom.2012.03.022
State	Published - 5 Aug 2012
Externally published	Yes

Keywords

Catalysis
Fluorine compounds
Palladium
Regioselectivity
Sonogashira reaction

ASJC Scopus subject areas

Catalysis
General Chemistry
Process Chemistry and Technology

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10.1016/j.catcom.2012.03.022

Cite this

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title = "Site-selective Sonogashira reactions of 1,2-dibromo-3,5-difluorobenzene",

abstract = "A variety of mono- and diethynyl substituted fluorinated benzene derivatives was prepared by Sonogashira cross coupling reactions of 1,2-dibromo-3,5-difluorobenzene. The reactions proceed with very good site-selectivity in favor of position 1, due to electronic and steric reasons.",

keywords = "Catalysis, Fluorine compounds, Palladium, Regioselectivity, Sonogashira reaction",

author = "Sebastian Reimann and Peter Ehlers and Muhammad Sharif and Kai Wittler and Anke Spannenberg and Ralf Ludwig and Peter Langer",

year = "2012",

month = aug,

day = "5",

doi = "10.1016/j.catcom.2012.03.022",

language = "English",

volume = "25",

pages = "142--147",

journal = "Catalysis Communications",

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T1 - Site-selective Sonogashira reactions of 1,2-dibromo-3,5-difluorobenzene

AU - Reimann, Sebastian

AU - Ehlers, Peter

AU - Sharif, Muhammad

AU - Wittler, Kai

AU - Spannenberg, Anke

AU - Ludwig, Ralf

AU - Langer, Peter

PY - 2012/8/5

Y1 - 2012/8/5

N2 - A variety of mono- and diethynyl substituted fluorinated benzene derivatives was prepared by Sonogashira cross coupling reactions of 1,2-dibromo-3,5-difluorobenzene. The reactions proceed with very good site-selectivity in favor of position 1, due to electronic and steric reasons.

AB - A variety of mono- and diethynyl substituted fluorinated benzene derivatives was prepared by Sonogashira cross coupling reactions of 1,2-dibromo-3,5-difluorobenzene. The reactions proceed with very good site-selectivity in favor of position 1, due to electronic and steric reasons.

KW - Catalysis

KW - Fluorine compounds

KW - Palladium

KW - Regioselectivity

KW - Sonogashira reaction

UR - https://www.scopus.com/pages/publications/84862563723

U2 - 10.1016/j.catcom.2012.03.022

DO - 10.1016/j.catcom.2012.03.022

M3 - Article

AN - SCOPUS:84862563723

SN - 1566-7367

VL - 25

SP - 142

EP - 147

JO - Catalysis Communications

JF - Catalysis Communications

ER -

Site-selective Sonogashira reactions of 1,2-dibromo-3,5-difluorobenzene

Abstract

Keywords

ASJC Scopus subject areas

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