Simultaneous detection of dopamine and ascorbic acid in urine using the H-point standard addition method

E. Y. Hashem, Ahmed M. El-Zohry

Research output: Contribution to journalArticlepeer-review

Abstract

A highly sensitive H-point standard addition method (HPSAM) was investigated for identification of dopamine and ascorbic acid in some synthetic and pharmaceutical samples in an aqueous medium at pH 9. 2 using a universal buffer. The most suitable wavelengths for dopamine and ascorbic acid detection are 260:271 nm and 248:270 nm respectively. Recovery values are between 99. 0-101 %. Also, the effect of most common interferents was studied. Detection ranges for dopamine and ascorbic acid are 2·10-6-5·10-5 M and 6·10-6-3·10-5 M respectively with an RSD range between 1. 3 and 2. 0 %. The method was used to determine both reagents in real and synthesized samples.

Original languageEnglish
Pages (from-to)424-430
Number of pages7
JournalJournal of Applied Spectroscopy
Volume79
Issue number3
DOIs
StatePublished - Jul 2012
Externally publishedYes

Keywords

  • HPSAM
  • UV
  • ascorbic acid
  • dopamine
  • pharmaceutical samples
  • urine samples

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Spectroscopy

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