Abstract
Zinc oxide nanoparticles (ZnO NPs) have attracted great attention because of their superior optical properties and wide application in biomedical science. However, little is known about the anticandidal activity of ZnO NPs against Candida albicans (C. albicans). This study was designed to develop the green approach to synthesize ZnO NPs using egg white (denoted as EtZnO NPs) and investigated its possible mechanism of antimicrobial activity against C. albicans 077. It was also notable that anticandidal activity of EtZnO NPs is correlated with reactive oxygen species (ROS) production in a dose dependent manner. Protection of histidine against ROS clearly suggests the implication of ROS in anticandidal activity of EtZnO NPs. This green approach based on egg white-mediated synthesis of ZnO NPs paves the way for developing cost effective, eco-friendly and promising antimicrobial nanomaterial for applications in medicine.
| Original language | English |
|---|---|
| Article number | 035015 |
| Journal | Advances in Natural Sciences: Nanoscience and Nanotechnology |
| Volume | 4 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2013 |
| Externally published | Yes |
Keywords
- Anticandidal
- Candida albicans
- Nanoparticles
- ROS
ASJC Scopus subject areas
- General Materials Science
- Industrial and Manufacturing Engineering
- Electrical and Electronic Engineering
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