Recyclable hydrophilic-hydrophobic micropatterns on glass for microarray applications

Hua Zhang; Yong Yeow Lee; Kwong Joo Leck; Namyong Y. Kim; Jackie Y. Ying

doi:10.1021/la063759i

Recyclable hydrophilic-hydrophobic micropatterns on glass for microarray applications

Hua Zhang, Yong Yeow Lee, Kwong Joo Leck, Namyong Y. Kim^*, Jackie Y. Ying

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

A novel method for fabricating recyclable hydrophilic-hydrophobic micropatterns on glass chips is presented. TiO_x patterns (100-2000 μm) were sputtered on glass chips via a through-hole mask. The patterned chips were then vapor-coated with fluoroalkylsilane, for example, (heptadecafluoro-1,1,2,2-tetrahydrodecyl)triethoxysilane (FTES) to form a hydrophobic coating layer. The fluoroalkyl chain of FTES film on TiO_x patterns was photocleaved under UV irradiation, exposing the fresh hydrophilic TiO_x patterns. The resulting chip could be used multiple times by repeating the coating and photocleaving processes with negligible deterioration of the hydrophobic FTES film coated on glass. If desired, bare glass patterns could also be generated by removing the TiO_x patterns with KOH. The patterned glass chips have been successfully used for microarray fabrication.

Original language	English
Pages (from-to)	4728-4731
Number of pages	4
Journal	Langmuir
Volume	23
Issue number	9
DOIs	https://doi.org/10.1021/la063759i
State	Published - 24 Apr 2007
Externally published	Yes

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

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10.1021/la063759i

Cite this

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title = "Recyclable hydrophilic-hydrophobic micropatterns on glass for microarray applications",

abstract = "A novel method for fabricating recyclable hydrophilic-hydrophobic micropatterns on glass chips is presented. TiOx patterns (100-2000 μm) were sputtered on glass chips via a through-hole mask. The patterned chips were then vapor-coated with fluoroalkylsilane, for example, (heptadecafluoro-1,1,2,2-tetrahydrodecyl)triethoxysilane (FTES) to form a hydrophobic coating layer. The fluoroalkyl chain of FTES film on TiOx patterns was photocleaved under UV irradiation, exposing the fresh hydrophilic TiOx patterns. The resulting chip could be used multiple times by repeating the coating and photocleaving processes with negligible deterioration of the hydrophobic FTES film coated on glass. If desired, bare glass patterns could also be generated by removing the TiOx patterns with KOH. The patterned glass chips have been successfully used for microarray fabrication.",

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T1 - Recyclable hydrophilic-hydrophobic micropatterns on glass for microarray applications

AU - Zhang, Hua

AU - Lee, Yong Yeow

AU - Leck, Kwong Joo

AU - Kim, Namyong Y.

AU - Ying, Jackie Y.

PY - 2007/4/24

Y1 - 2007/4/24

N2 - A novel method for fabricating recyclable hydrophilic-hydrophobic micropatterns on glass chips is presented. TiOx patterns (100-2000 μm) were sputtered on glass chips via a through-hole mask. The patterned chips were then vapor-coated with fluoroalkylsilane, for example, (heptadecafluoro-1,1,2,2-tetrahydrodecyl)triethoxysilane (FTES) to form a hydrophobic coating layer. The fluoroalkyl chain of FTES film on TiOx patterns was photocleaved under UV irradiation, exposing the fresh hydrophilic TiOx patterns. The resulting chip could be used multiple times by repeating the coating and photocleaving processes with negligible deterioration of the hydrophobic FTES film coated on glass. If desired, bare glass patterns could also be generated by removing the TiOx patterns with KOH. The patterned glass chips have been successfully used for microarray fabrication.

AB - A novel method for fabricating recyclable hydrophilic-hydrophobic micropatterns on glass chips is presented. TiOx patterns (100-2000 μm) were sputtered on glass chips via a through-hole mask. The patterned chips were then vapor-coated with fluoroalkylsilane, for example, (heptadecafluoro-1,1,2,2-tetrahydrodecyl)triethoxysilane (FTES) to form a hydrophobic coating layer. The fluoroalkyl chain of FTES film on TiOx patterns was photocleaved under UV irradiation, exposing the fresh hydrophilic TiOx patterns. The resulting chip could be used multiple times by repeating the coating and photocleaving processes with negligible deterioration of the hydrophobic FTES film coated on glass. If desired, bare glass patterns could also be generated by removing the TiOx patterns with KOH. The patterned glass chips have been successfully used for microarray fabrication.

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Recyclable hydrophilic-hydrophobic micropatterns on glass for microarray applications

Abstract

ASJC Scopus subject areas

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