Abstract
Supramolecules-based drug delivery has attracted significant recent research attention as it could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among the different supramolecules and assemblies, the macrocycles and the supramolecular hydrogels are the two important categories investigated to a greater extent. Here, we provide the most recent advancements in these categories. Under macrocycles, reports on drug delivery by cyclodextrins, cucurbiturils, calixarenes/pillararenes, crown ethers and porphyrins are detailed. The second category discusses the supramolecular hydrogels of macrocycles/polymers and low molecular weight gelators. The updated information provided could be helpful to advance R & D in this vital area.
| Original language | English |
|---|---|
| Article number | e202200053 |
| Journal | Chemical Record |
| Volume | 22 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2022 |
Bibliographical note
Publisher Copyright:© 2022 The Chemical Society of Japan & Wiley-VCH GmbH.
Keywords
- Cyclodextrins
- Drug delivery
- Hydrogels
- Macrocycles
- Supramolecules and Assemblies
ASJC Scopus subject areas
- General Chemistry
- Biochemistry
- General Chemical Engineering
- Materials Chemistry