Recent applications of asymmetric organocatalytic annulation reactions in natural product synthesis

Nengzhong Wang, Zugen Wu, Junjie Wang, Nisar Ullah*, Yixin Lu*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations

Abstract

The past two decades have witnessed remarkable growth of asymmetric organocatalysis, which is now a firmly established synthetic tool, serving as a powerful platform for the production of chiral molecules. Ring structures are ubiquitous in organic compounds, and, in the context of natural product synthesis, strategic construction of ring motifs is often crucial, fundamentally impacting the eventual fate of the whole synthetic plan. In this review, we provide a comprehensive and updated summary of asymmetric organocatalytic annulation reactions; in particular, the application of these annulation strategies in natural product synthesis will be highlighted.

Original languageEnglish
Pages (from-to)9766-9793
Number of pages28
JournalChemical Society Reviews
Volume50
Issue number17
DOIs
StatePublished - 7 Sep 2021

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry.

ASJC Scopus subject areas

  • General Chemistry

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