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Recent Advances of Silver-Based Coordination Polymers on Antibacterial Applications

  • Wenfeng Zhang
  • , Gaomin Ye
  • , Donghui Liao
  • , Xuelin Chen
  • , Chengyu Lu*
  • , Alireza Nezamzadeh-Ejhieh
  • , M. Shahnawaz Khan
  • , Jianqiang Liu
  • , Ying Pan*
  • , Zhong Dai*
  • *Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

130 Scopus citations

Abstract

With the continuous evolution of bacteria and the constant use of traditional antibiotics, the emergence of drug-resistant bacteria and super viruses has attracted worldwide attention. Antimicrobial therapy has become the most popular and important research field at present. Coordination Polymer (CP) and/or metal-organic framework (MOF) platforms have the advantages of a high biocompatibility, biodegradability, and non-toxicity, have a great antibacterial potential and have been widely used in antibacterial treatment. This paper reviewed the mechanism and antibacterial effect of three typical MOFs (pure Ag-MOFs, hybrid Ag-MOFs, and Ag-containing-polymer @MOFs) in silver-based coordination polymers. At the same time, the existing shortcomings and future views are briefly discussed. The study on the antibacterial efficacy and mechanism of Ag-MOFs can provide a better basis for its clinical application and, meanwhile, open up a novel strategy for the preparation of more advanced Ag-contained materials with antibacterial characteristics.

Original languageEnglish
Article number7166
JournalMolecules
Volume27
Issue number21
DOIs
StatePublished - Nov 2022
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2022 by the authors.

Keywords

  • anti-bacterial effect
  • anti-bacterial mechanism
  • metal-organic frameworks
  • silver

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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