Pyrano- and dihydrofurano-isoflavones from Milletia thonningii

William A. Asomaning; Charles Amoako; Isaac V. Oppong; William R. Phillips; Ivan Addae-Mensah; Emmanuel Y. Osei-Twum; Reiner Waibel; Hans Achenbach

doi:10.1016/0031-9422(95)00164-3

Pyrano- and dihydrofurano-isoflavones from Milletia thonningii

William A. Asomaning^*, Charles Amoako, Isaac V. Oppong, William R. Phillips, Ivan Addae-Mensah, Emmanuel Y. Osei-Twum, Reiner Waibel, Hans Achenbach

^*Corresponding author for this work

King Fahd University of Petroleum & Minerals

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The petrol extract of the root bark of Milletia thonningii afforded β-amyrin and O,O-dimethylalpinumisoflavone, together with the new compounds 5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone and thonninginisoflavone. The structures were determined by spectroscopic methods and partly by chemical interconversions. The absolute configuration of thonninginisoflavone was established by chiroptical studies. The crude extract and some of the pure compounds were active in the brine shrimp lethality bioassay.

Original language	English
Pages (from-to)	1215-1218
Number of pages	4
Journal	Phytochemistry
Volume	39
Issue number	5
DOIs	https://doi.org/10.1016/0031-9422(95)00164-3
State	Published - Jul 1995

Bibliographical note

Funding Information:
Acknowledgements--A study leave with pay granted to one of us (C.A.) by the Ministry of Education of Ghana through the Ghana Education Service is gratefully acknowledged. Thanks are also due to the Deutsche For-schungsgemeinschaft and the Fonds der Chemischen In-dustrie in Germany for financial support.

Keywords

5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone
Leguminosae
Milletia thonningii
O,O-diemthylalpinumisoflavone
isoflavones
root bark
thonninginisoflavone

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/0031-9422(95)00164-3

Cite this

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title = "Pyrano- and dihydrofurano-isoflavones from Milletia thonningii",

abstract = "The petrol extract of the root bark of Milletia thonningii afforded β-amyrin and O,O-dimethylalpinumisoflavone, together with the new compounds 5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone and thonninginisoflavone. The structures were determined by spectroscopic methods and partly by chemical interconversions. The absolute configuration of thonninginisoflavone was established by chiroptical studies. The crude extract and some of the pure compounds were active in the brine shrimp lethality bioassay.",

keywords = "5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone, Leguminosae, Milletia thonningii, O,O-diemthylalpinumisoflavone, isoflavones, root bark, thonninginisoflavone",

author = "Asomaning, {William A.} and Charles Amoako and Oppong, {Isaac V.} and Phillips, {William R.} and Ivan Addae-Mensah and Osei-Twum, {Emmanuel Y.} and Reiner Waibel and Hans Achenbach",

note = "Funding Information: Acknowledgements--A study leave with pay granted to one of us (C.A.) by the Ministry of Education of Ghana through the Ghana Education Service is gratefully acknowledged. Thanks are also due to the Deutsche For-schungsgemeinschaft and the Fonds der Chemischen In-dustrie in Germany for financial support.",

year = "1995",

month = jul,

doi = "10.1016/0031-9422(95)00164-3",

language = "English",

volume = "39",

pages = "1215--1218",

journal = "Phytochemistry",

issn = "0031-9422",

number = "5",

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T1 - Pyrano- and dihydrofurano-isoflavones from Milletia thonningii

AU - Asomaning, William A.

AU - Amoako, Charles

AU - Oppong, Isaac V.

AU - Phillips, William R.

AU - Addae-Mensah, Ivan

AU - Osei-Twum, Emmanuel Y.

AU - Waibel, Reiner

AU - Achenbach, Hans

N1 - Funding Information: Acknowledgements--A study leave with pay granted to one of us (C.A.) by the Ministry of Education of Ghana through the Ghana Education Service is gratefully acknowledged. Thanks are also due to the Deutsche For-schungsgemeinschaft and the Fonds der Chemischen In-dustrie in Germany for financial support.

PY - 1995/7

Y1 - 1995/7

N2 - The petrol extract of the root bark of Milletia thonningii afforded β-amyrin and O,O-dimethylalpinumisoflavone, together with the new compounds 5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone and thonninginisoflavone. The structures were determined by spectroscopic methods and partly by chemical interconversions. The absolute configuration of thonninginisoflavone was established by chiroptical studies. The crude extract and some of the pure compounds were active in the brine shrimp lethality bioassay.

AB - The petrol extract of the root bark of Milletia thonningii afforded β-amyrin and O,O-dimethylalpinumisoflavone, together with the new compounds 5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone and thonninginisoflavone. The structures were determined by spectroscopic methods and partly by chemical interconversions. The absolute configuration of thonninginisoflavone was established by chiroptical studies. The crude extract and some of the pure compounds were active in the brine shrimp lethality bioassay.

KW - 5-O-methyl-4′-O-(3-methyl-2-butenyl)alpinumisoflavone

KW - Leguminosae

KW - Milletia thonningii

KW - O,O-diemthylalpinumisoflavone

KW - isoflavones

KW - root bark

KW - thonninginisoflavone

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U2 - 10.1016/0031-9422(95)00164-3

DO - 10.1016/0031-9422(95)00164-3

M3 - Article

AN - SCOPUS:0028887828

SN - 0031-9422

VL - 39

SP - 1215

EP - 1218

JO - Phytochemistry

JF - Phytochemistry

IS - 5

ER -

Pyrano- and dihydrofurano-isoflavones from Milletia thonningii

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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