Potentiometric determination of pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6, 7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis

Kadir Ibaoglu; Hayati Sari; Mustafa Tuzen; Durali Mendil; Mustafa Soylak

Potentiometric determination of pK_a values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6, 7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis

Kadir Ibaoglu, Hayati Sari^*, Mustafa Tuzen, Durali Mendil, Mustafa Soylak

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The pK_a values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10- dihydro-acridine-2,3,6,7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis were determined by Molspin potentiometric titration at 25°C in the presence of 0.1 mol dm^-3 NaCl. The pK_a values were calculated using SUPERQUAD computer program. Initially deprotonation occurs in carboxylic groups, then at the nitrogen atom of the alkyl group, and finally at the hydroxylic groups of TPAT. The following pK_a values were computed: 2.65, 3.36, 4.08, 5.43, 6.84, 9.30, 10.42 and 10.53.

Original language	English
Pages (from-to)	635-642
Number of pages	8
Journal	Chemia Analityczna
Volume	49
Issue number	5
State	Published - 2004
Externally published	Yes

Keywords

Dissociation constants
Molspin
Polyphenolic acids
Potentiometry
SUPERQUAD

ASJC Scopus subject areas

Analytical Chemistry

Cite this

@article{59d59a0de0704b1c8e93e9bd8053b800,

title = "Potentiometric determination of pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6, 7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis",

abstract = "The pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10- dihydro-acridine-2,3,6,7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis were determined by Molspin potentiometric titration at 25°C in the presence of 0.1 mol dm-3 NaCl. The pKa values were calculated using SUPERQUAD computer program. Initially deprotonation occurs in carboxylic groups, then at the nitrogen atom of the alkyl group, and finally at the hydroxylic groups of TPAT. The following pKa values were computed: 2.65, 3.36, 4.08, 5.43, 6.84, 9.30, 10.42 and 10.53.",

keywords = "Dissociation constants, Molspin, Polyphenolic acids, Potentiometry, SUPERQUAD",

author = "Kadir Ibaoglu and Hayati Sari and Mustafa Tuzen and Durali Mendil and Mustafa Soylak",

year = "2004",

language = "English",

volume = "49",

pages = "635--642",

journal = "Chemia Analityczna",

issn = "0009-2223",

publisher = "Polskie Towarzystwo Chemiczne",

number = "5",

}

TY - JOUR

T1 - Potentiometric determination of pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6, 7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis

AU - Ibaoglu, Kadir

AU - Sari, Hayati

AU - Tuzen, Mustafa

AU - Mendil, Durali

AU - Soylak, Mustafa

PY - 2004

Y1 - 2004

N2 - The pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10- dihydro-acridine-2,3,6,7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis were determined by Molspin potentiometric titration at 25°C in the presence of 0.1 mol dm-3 NaCl. The pKa values were calculated using SUPERQUAD computer program. Initially deprotonation occurs in carboxylic groups, then at the nitrogen atom of the alkyl group, and finally at the hydroxylic groups of TPAT. The following pKa values were computed: 2.65, 3.36, 4.08, 5.43, 6.84, 9.30, 10.42 and 10.53.

AB - The pKa values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10- dihydro-acridine-2,3,6,7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis were determined by Molspin potentiometric titration at 25°C in the presence of 0.1 mol dm-3 NaCl. The pKa values were calculated using SUPERQUAD computer program. Initially deprotonation occurs in carboxylic groups, then at the nitrogen atom of the alkyl group, and finally at the hydroxylic groups of TPAT. The following pKa values were computed: 2.65, 3.36, 4.08, 5.43, 6.84, 9.30, 10.42 and 10.53.

KW - Dissociation constants

KW - Molspin

KW - Polyphenolic acids

KW - Potentiometry

KW - SUPERQUAD

UR - https://www.scopus.com/pages/publications/19344367235

M3 - Article

AN - SCOPUS:19344367235

SN - 0009-2223

VL - 49

SP - 635

EP - 642

JO - Chemia Analityczna

JF - Chemia Analityczna

IS - 5