Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate

J. S. Hansen; J. B. Christensen; T. I. Solling; P. Jakobsen; T. Hoeg-Jensen

doi:10.1016/j.tet.2010.11.062

Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate

J. S. Hansen, J. B. Christensen, T. I. Solling, P. Jakobsen, T. Hoeg-Jensen

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Ortho-substituted aryl monoboronic acids have been found to have improved selectivity for d-glucose compared to d-fructose and l-lactate. These findings are supported by computational studies on the B3LYP/6-31G(d) level using Gaussian. This finding is of interest for development of boronate based d-glucose sensors.

Original language	English
Pages (from-to)	1334-1340
Number of pages	7
Journal	Tetrahedron
Volume	67
Issue number	6
DOIs	https://doi.org/10.1016/j.tet.2010.11.062
State	Published - 11 Feb 2011
Externally published	Yes

Bibliographical note

Funding Information:
Financial support from the University of Copenhagen, Department of Chemistry , and from Novo Nordisk A/S is gratefully acknowledged.

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2010.11.062

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title = "Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate",

abstract = "Ortho-substituted aryl monoboronic acids have been found to have improved selectivity for d-glucose compared to d-fructose and l-lactate. These findings are supported by computational studies on the B3LYP/6-31G(d) level using Gaussian. This finding is of interest for development of boronate based d-glucose sensors.",

author = "Hansen, \{J. S.\} and Christensen, \{J. B.\} and Solling, \{T. I.\} and P. Jakobsen and T. Hoeg-Jensen",

note = "Funding Information: Financial support from the University of Copenhagen, Department of Chemistry , and from Novo Nordisk A/S is gratefully acknowledged.",

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AU - Hansen, J. S.

AU - Christensen, J. B.

AU - Solling, T. I.

AU - Jakobsen, P.

AU - Hoeg-Jensen, T.

N1 - Funding Information: Financial support from the University of Copenhagen, Department of Chemistry , and from Novo Nordisk A/S is gratefully acknowledged.

PY - 2011/2/11

Y1 - 2011/2/11

N2 - Ortho-substituted aryl monoboronic acids have been found to have improved selectivity for d-glucose compared to d-fructose and l-lactate. These findings are supported by computational studies on the B3LYP/6-31G(d) level using Gaussian. This finding is of interest for development of boronate based d-glucose sensors.

AB - Ortho-substituted aryl monoboronic acids have been found to have improved selectivity for d-glucose compared to d-fructose and l-lactate. These findings are supported by computational studies on the B3LYP/6-31G(d) level using Gaussian. This finding is of interest for development of boronate based d-glucose sensors.

UR - https://www.scopus.com/pages/publications/78751579040

U2 - 10.1016/j.tet.2010.11.062

DO - 10.1016/j.tet.2010.11.062

M3 - Article

AN - SCOPUS:78751579040

SN - 0040-4020

VL - 67

SP - 1334

EP - 1340

JO - Tetrahedron

JF - Tetrahedron

IS - 6

ER -

Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate

Abstract

Bibliographical note

ASJC Scopus subject areas

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