One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Krishna M. Deshmukh; Ziyauddin S. Qureshi; Nitin S. Nandurkar; Bhalchandra M. Bhanage

doi:10.1139/V08-173

One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Krishna M. Deshmukh
, Ziyauddin S. Qureshi
, Nitin S. Nandurkar
, Bhalchandra M. Bhanage

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO₄]) as a Brønsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.

Original language	English
Pages (from-to)	401-405
Number of pages	5
Journal	Canadian Journal of Chemistry
Volume	87
Issue number	2
DOIs	https://doi.org/10.1139/V08-173
State	Published - Feb 2009
Externally published	Yes

Keywords

Ionic liquids
Multicomponent reactions
One-pot synthesis
β-amido ketones

ASJC Scopus subject areas

Catalysis
General Chemistry
Organic Chemistry

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10.1139/V08-173

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title = "One-pot synthesis of β-amido ketones using br{\o}nsted acidic ionic liquid as an efficient and reusable catalyst",

abstract = "An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO4]) as a Br{\o}nsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.",

keywords = "Ionic liquids, Multicomponent reactions, One-pot synthesis, β-amido ketones",

author = "Deshmukh, \{Krishna M.\} and Qureshi, \{Ziyauddin S.\} and Nandurkar, \{Nitin S.\} and Bhanage, \{Bhalchandra M.\}",

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doi = "10.1139/V08-173",

language = "English",

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AU - Deshmukh, Krishna M.

AU - Qureshi, Ziyauddin S.

AU - Nandurkar, Nitin S.

AU - Bhanage, Bhalchandra M.

PY - 2009/2

Y1 - 2009/2

N2 - An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO4]) as a Brønsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.

AB - An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO4]) as a Brønsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.

KW - Ionic liquids

KW - Multicomponent reactions

KW - One-pot synthesis

KW - β-amido ketones

UR - https://www.scopus.com/pages/publications/67650337850

U2 - 10.1139/V08-173

DO - 10.1139/V08-173

M3 - Article

AN - SCOPUS:67650337850

SN - 0008-4042

VL - 87

SP - 401

EP - 405

JO - Canadian Journal of Chemistry

JF - Canadian Journal of Chemistry

IS - 2

ER -

One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Abstract

Keywords

ASJC Scopus subject areas

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