One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Krishna M. Deshmukh; Ziyauddin S. Qureshi; Nitin S. Nandurkar; Bhalchandra M. Bhanage

doi:10.1139/V08-173

One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Krishna M. Deshmukh, Ziyauddin S. Qureshi, Nitin S. Nandurkar, Bhalchandra M. Bhanage

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO₄]) as a Brønsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.

Original language	English
Pages (from-to)	401-405
Number of pages	5
Journal	Canadian Journal of Chemistry
Volume	87
Issue number	2
DOIs	https://doi.org/10.1139/V08-173
State	Published - Feb 2009
Externally published	Yes

Keywords

Ionic liquids
Multicomponent reactions
One-pot synthesis
β-amido ketones

ASJC Scopus subject areas

Catalysis
General Chemistry
Organic Chemistry

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10.1139/V08-173

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abstract = "An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO4]) as a Br{\o}nsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.",

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AU - Deshmukh, Krishna M.

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AU - Nandurkar, Nitin S.

AU - Bhanage, Bhalchandra M.

PY - 2009/2

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AB - An efficient protocol was developed for one-pot condensation of an aldehyde, ketone, acetyl chloride, and nitriles catalyzed by a stable and reusable 1-methyl-imidazolium hydrogen sulfate ([Hmim][HSO4]) as a Brønsted acidic ionic liquid. The system tolerated a variety of functional groups affording the corresponding β-amido ketones in moderate to good yields under milder operating conditions.

KW - Ionic liquids

KW - Multicomponent reactions

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KW - β-amido ketones

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JF - Canadian Journal of Chemistry

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ER -

One-pot synthesis of β-amido ketones using brønsted acidic ionic liquid as an efficient and reusable catalyst

Abstract

Keywords

ASJC Scopus subject areas

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