One pot light assisted green synthesis, storage and antimicrobial activity of dextran stabilized silver nanoparticles

  • Muhammad Ajaz Hussain*
  • , Abdullah Shah
  • , Ibrahim Jantan
  • , Muhammad Nawaz Tahir
  • , Muhammad Raza Shah
  • , Riaz Ahmed
  • , Syed Nasir Abbas Bukhari
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Background: Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report green synthesis of silver nanoparticles (Ag NPs) mediated with dextran. Dextran was used as a stabilizer and capping agent to synthesize Ag NPs using silver nitrate (AgNO3) under diffused sunlight conditions. Results: UV-vis spectra of as synthesized Ag nanoparticles showed characteristic surface plasmon band in the range from ~405-452 nm. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) studies showed spherical Ag NPs in the size regime of ~50-70 nm. Face centered cubic lattice of Ag NPs was confirmed by powder X-ray diffraction (PXRD). FT-IR spectroscopy confirmed that dextran not only acts as reducing agent but also functionalizes the surfaces of Ag NPs to make very stable dispersions. Moreover, on drying, the solution of dextran stabilized Ag NPs resulted in the formation of thin films which were found stable over months with no change in the plasmon band of pristine Ag NPs. The antimicrobial assay of the as synthesized Ag NPs showed remarkable activity. Conclusion: Being significantly active against microbes, the Ag NPs can be explored for antimicrobial medical devices.

Original languageEnglish
Article number53
JournalJournal of Nanobiotechnology
Volume12
Issue number1
DOIs
StatePublished - 3 Dec 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Hussain et al.; licensee BioMed Central Ltd.

Keywords

  • Ag nanoparticles
  • Antimicrobial activity
  • Diffused sun light
  • Storage of nanoparticles

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Molecular Medicine
  • Biomedical Engineering
  • Applied Microbiology and Biotechnology
  • Pharmaceutical Science

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