Niosome-Based Anticancer Therapies

Niosomes are the non-ionic self-assembled bilayer vesicles stabilized with cholesterol with or without charge imparting agents. The niosomes can load hydrophilic and hydrophobic drugs. Niosomes are more stable and economical than liposomes. Niosomes have been used to load different types of drugs, i.e., anti-inflammatory, antivirals, antimicrobials, anticancer, etc., the niosomes have the capacity to increase the solubility of the poorly water-soluble drugs soluble. Among these, anticancer drugs are the best candidates to be loaded in niosomes. Many anticancer drugs are poorly water-soluble, resulting in low bioavailability and more toxicity. Niosomes show high entrapment efficiencies with increased solubility, bioavailability, and increased antiproliferative with the least toxicity of the drugs. Niosomes are the best nanocarrier for the delivery of all types of drugs, especially cytotoxic drugs.