TY - JOUR
T1 - Nb/Starch-Doped ZnO Nanostructures for Polluted Water Treatment and Antimicrobial Applications
T2 - Molecular Docking Analysis
AU - Ikram, Muhammad
AU - Shahid, Huma
AU - Haider, Junaid
AU - Haider, Ali
AU - Naz, Sadia
AU - Ul-Hamid, Anwar
AU - Shahzadi, Iram
AU - Naz, Misbah
AU - Nabgan, Walid
AU - Ali, Salamat
N1 - Publisher Copyright:
© 2022 The Authors. Published by American Chemical Society.
PY - 2022/11/1
Y1 - 2022/11/1
N2 - Nb/starch-doped ZnO quantum dots (QDs) were prepared by a coprecipitation route. A fixed quantity of starch (st) and different concentrations (2 and 4%) of niobium (Nb) were doped in a ZnO lattice. To gain a better understanding of synthesized nanostructures, a systematic study was carried out utilizing several characterization methods. The goal of this research was to undertake methylene blue (MB) dye degradation with a synthetic material and also study its antibacterial properties. The phase structure, morphology, functional groups, optical properties, and elemental compositions of synthesized samples were investigated. Our study showed that ZnO QDs enhanced photocatalytic activity (PCA), resulting in effective MB degradation, in addition to showing good antimicrobial activity against Gram-negative relative to Gram-positive bacteria. Molecular docking study findings were in good agreement with the observed in vitro bactericidal potential and suggested ZnO, st-ZnO, and Nb/st-ZnO as possible inhibitors against dihydrofolate reductase (DHFRE. coli) and DNA gyraseE. coli.
AB - Nb/starch-doped ZnO quantum dots (QDs) were prepared by a coprecipitation route. A fixed quantity of starch (st) and different concentrations (2 and 4%) of niobium (Nb) were doped in a ZnO lattice. To gain a better understanding of synthesized nanostructures, a systematic study was carried out utilizing several characterization methods. The goal of this research was to undertake methylene blue (MB) dye degradation with a synthetic material and also study its antibacterial properties. The phase structure, morphology, functional groups, optical properties, and elemental compositions of synthesized samples were investigated. Our study showed that ZnO QDs enhanced photocatalytic activity (PCA), resulting in effective MB degradation, in addition to showing good antimicrobial activity against Gram-negative relative to Gram-positive bacteria. Molecular docking study findings were in good agreement with the observed in vitro bactericidal potential and suggested ZnO, st-ZnO, and Nb/st-ZnO as possible inhibitors against dihydrofolate reductase (DHFRE. coli) and DNA gyraseE. coli.
UR - https://www.scopus.com/pages/publications/85140912890
U2 - 10.1021/acsomega.2c05569
DO - 10.1021/acsomega.2c05569
M3 - Article
AN - SCOPUS:85140912890
SN - 2470-1343
VL - 7
SP - 39347
EP - 39361
JO - ACS Omega
JF - ACS Omega
IS - 43
ER -
