Nanostructure Processing of Hydroxyapatite-based Bioceramics

Edward S. Ahn; Nathaniel J. Gleason; Atsushi Nakahira; Jackie Y. Ying

doi:10.1021/nl0055299

Nanostructure Processing of Hydroxyapatite-based Bioceramics

Edward S. Ahn
, Nathaniel J. Gleason
, Atsushi Nakahira
, Jackie Y. Ying^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

258 Scopus citations

Abstract

Nanostructure processing was applied to derive hydroxyapatite and hydroxyapatite-zirconia bioceramics with ultrafine microstructures and significantly improved mechanical properties for orthopedic and dental implant applications. Despite its attractive bioactivity, hydroxyapatite (HAP) has been limited in applications due to the poor processability and mechanical strength of the conventional material. Through nanostructure processing, high-strength HAP has been obtained by pressure-assisted sintering. To further toughen the HAP matrix, nanocrystalline yttria-stabilized zirconia (YSZ) dispersoids have been introduced during HAP precipitation. The nanostructured HAP and HAP-YSZ composites demonstrated excellent chemical and microstructural uniformity and mechanical properties, compared to conventional coarse-grained systems.

Original language	English
Pages (from-to)	149-153
Number of pages	5
Journal	Nano Letters
Volume	1
Issue number	3
DOIs	https://doi.org/10.1021/nl0055299
State	Published - Mar 2001
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
General Chemistry
General Materials Science
Condensed Matter Physics
Mechanical Engineering

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title = "Nanostructure Processing of Hydroxyapatite-based Bioceramics",

abstract = "Nanostructure processing was applied to derive hydroxyapatite and hydroxyapatite-zirconia bioceramics with ultrafine microstructures and significantly improved mechanical properties for orthopedic and dental implant applications. Despite its attractive bioactivity, hydroxyapatite (HAP) has been limited in applications due to the poor processability and mechanical strength of the conventional material. Through nanostructure processing, high-strength HAP has been obtained by pressure-assisted sintering. To further toughen the HAP matrix, nanocrystalline yttria-stabilized zirconia (YSZ) dispersoids have been introduced during HAP precipitation. The nanostructured HAP and HAP-YSZ composites demonstrated excellent chemical and microstructural uniformity and mechanical properties, compared to conventional coarse-grained systems.",

author = "Ahn, \{Edward S.\} and Gleason, \{Nathaniel J.\} and Atsushi Nakahira and Ying, \{Jackie Y.\}",

year = "2001",

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doi = "10.1021/nl0055299",

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journal = "Nano Letters",

issn = "1530-6984",

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T1 - Nanostructure Processing of Hydroxyapatite-based Bioceramics

AU - Ahn, Edward S.

AU - Gleason, Nathaniel J.

AU - Nakahira, Atsushi

AU - Ying, Jackie Y.

PY - 2001/3

Y1 - 2001/3

N2 - Nanostructure processing was applied to derive hydroxyapatite and hydroxyapatite-zirconia bioceramics with ultrafine microstructures and significantly improved mechanical properties for orthopedic and dental implant applications. Despite its attractive bioactivity, hydroxyapatite (HAP) has been limited in applications due to the poor processability and mechanical strength of the conventional material. Through nanostructure processing, high-strength HAP has been obtained by pressure-assisted sintering. To further toughen the HAP matrix, nanocrystalline yttria-stabilized zirconia (YSZ) dispersoids have been introduced during HAP precipitation. The nanostructured HAP and HAP-YSZ composites demonstrated excellent chemical and microstructural uniformity and mechanical properties, compared to conventional coarse-grained systems.

AB - Nanostructure processing was applied to derive hydroxyapatite and hydroxyapatite-zirconia bioceramics with ultrafine microstructures and significantly improved mechanical properties for orthopedic and dental implant applications. Despite its attractive bioactivity, hydroxyapatite (HAP) has been limited in applications due to the poor processability and mechanical strength of the conventional material. Through nanostructure processing, high-strength HAP has been obtained by pressure-assisted sintering. To further toughen the HAP matrix, nanocrystalline yttria-stabilized zirconia (YSZ) dispersoids have been introduced during HAP precipitation. The nanostructured HAP and HAP-YSZ composites demonstrated excellent chemical and microstructural uniformity and mechanical properties, compared to conventional coarse-grained systems.

UR - https://www.scopus.com/pages/publications/0000317734

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DO - 10.1021/nl0055299

M3 - Article

AN - SCOPUS:0000317734

SN - 1530-6984

VL - 1

SP - 149

EP - 153

JO - Nano Letters

JF - Nano Letters

IS - 3

ER -

Nanostructure Processing of Hydroxyapatite-based Bioceramics

Abstract

ASJC Scopus subject areas

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