NanoBio-tools for selective activation of Toll-like receptors (TLRs)

M. I. Shukoor; F. Natalio; N. Glube; M. N. Tahir; H. A. Therese; V. Ksenofontov; P. Theato; P. Langguts; J. P. Boissel; H. C. Schröder; W. E.G. Müller; W. Tremel

NanoBio-tools for selective activation of Toll-like receptors (TLRs)

M. I. Shukoor
, F. Natalio
, N. Glube
, M. N. Tahir
, H. A. Therese
, V. Ksenofontov
, P. Theato
, P. Langguts
, J. P. Boissel
, H. C. Schröder
, W. E.G. Müller
, W. Tremel^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The immobilization of polyinosinic-polycytidylic acid [poly(I:C)] on γ-Fe₂O₃ nanoparticles via the phosphoramidate route using a multifunctional polymer is reported. The dsRNA coupled nanoparticles were used to visualize the Toll-like (TLR3) receptors at the cell surface. The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques.

Original language	English
Title of host publication	Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages	505-508
Number of pages	4
State	Published - 2008

Publication series

Name	Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Volume	2

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer cells
Magnetic nanoparticles
Specific binding
TLR receptors
ds RNA Poly(IC)

ASJC Scopus subject areas

Mechanical Engineering

Cite this

Shukoor, M. I., Natalio, F., Glube, N., Tahir, M. N., Therese, H. A., Ksenofontov, V., Theato, P., Langguts, P., Boissel, J. P., Schröder, H. C., Müller, W. E. G., & Tremel, W. (2008). NanoBio-tools for selective activation of Toll-like receptors (TLRs). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (pp. 505-508). (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 2).

Shukoor, M. I. ; Natalio, F. ; Glube, N. et al. / NanoBio-tools for selective activation of Toll-like receptors (TLRs). Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. pp. 505-508 (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008).

@inproceedings{8e603cbaa0aa4692848282224a8d41f9,

title = "NanoBio-tools for selective activation of Toll-like receptors (TLRs)",

abstract = "The immobilization of polyinosinic-polycytidylic acid [poly(I:C)] on γ-Fe2O3 nanoparticles via the phosphoramidate route using a multifunctional polymer is reported. The dsRNA coupled nanoparticles were used to visualize the Toll-like (TLR3) receptors at the cell surface. The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques.",

keywords = "Cancer cells, Magnetic nanoparticles, Specific binding, TLR receptors, ds RNA Poly(IC)",

author = "Shukoor, \{M. I.\} and F. Natalio and N. Glube and Tahir, \{M. N.\} and Therese, \{H. A.\} and V. Ksenofontov and P. Theato and P. Langguts and Boissel, \{J. P.\} and Schr{\"o}der, \{H. C.\} and M{\"u}ller, \{W. E.G.\} and W. Tremel",

year = "2008",

language = "English",

isbn = "9781420085075",

series = "Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008",

pages = "505--508",

booktitle = "Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008",

}

Shukoor, MI, Natalio, F, Glube, N, Tahir, MN, Therese, HA, Ksenofontov, V, Theato, P, Langguts, P, Boissel, JP, Schröder, HC, Müller, WEG & Tremel, W 2008, NanoBio-tools for selective activation of Toll-like receptors (TLRs). in Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008, vol. 2, pp. 505-508.

NanoBio-tools for selective activation of Toll-like receptors (TLRs). / Shukoor, M. I.; Natalio, F.; Glube, N. et al.
Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. p. 505-508 (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - NanoBio-tools for selective activation of Toll-like receptors (TLRs)

AU - Shukoor, M. I.

AU - Natalio, F.

AU - Glube, N.

AU - Tahir, M. N.

AU - Therese, H. A.

AU - Ksenofontov, V.

AU - Theato, P.

AU - Langguts, P.

AU - Boissel, J. P.

AU - Schröder, H. C.

AU - Müller, W. E.G.

AU - Tremel, W.

PY - 2008

Y1 - 2008

N2 - The immobilization of polyinosinic-polycytidylic acid [poly(I:C)] on γ-Fe2O3 nanoparticles via the phosphoramidate route using a multifunctional polymer is reported. The dsRNA coupled nanoparticles were used to visualize the Toll-like (TLR3) receptors at the cell surface. The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques.

AB - The immobilization of polyinosinic-polycytidylic acid [poly(I:C)] on γ-Fe2O3 nanoparticles via the phosphoramidate route using a multifunctional polymer is reported. The dsRNA coupled nanoparticles were used to visualize the Toll-like (TLR3) receptors at the cell surface. The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques.

KW - Cancer cells

KW - Magnetic nanoparticles

KW - Specific binding

KW - TLR receptors

KW - ds RNA Poly(IC)

UR - https://www.scopus.com/pages/publications/52649105932

M3 - Conference contribution

AN - SCOPUS:52649105932

SN - 9781420085075

SN - 9781420085044

T3 - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008

SP - 505

EP - 508

BT - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008

ER -

Shukoor MI, Natalio F, Glube N, Tahir MN, Therese HA, Ksenofontov V et al. NanoBio-tools for selective activation of Toll-like receptors (TLRs). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. 2008. p. 505-508. (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008).

NanoBio-tools for selective activation of Toll-like receptors (TLRs)

Abstract

Publication series

UN SDGs

Keywords

ASJC Scopus subject areas

Fingerprint

Cite this