@inproceedings{ca18cda2776749fc8638771da6328932,
title = "Microfluidic device with asymmetric electrodes for cell and reagent delivery",
abstract = "We present the design and fabrication of a micro-electromechanical system (MEMS) device for cell and particle delivery using a combination of AC electrokinetic fluidic flow and negative dielectrophoresis (DEP) force. An array of interdigitated asymmetric microelectrode pairs were used in the planar device. The electrodes produced a net charge in the surrounding fluid, generating an AC electrokinetic fluidic motion. A non-uniform electric field with low actuation frequency from the microelectrode pairs resulted in a negative DEP force, which was responsible for pushing delivery particles away from sedimentation. The experimental results showed that the flow velocity increased rapidly from 267 μm/min to 394 μm/min when the applied frequency was increased from 10 kHz to 70 kHz for a cell-suspending medium buffer solution with a conductivity of 4.7 μS/cm. A maximum delivery velocity of 801 μm/min was obtained when the buffer conductivity was increased to 47 μS/cm with an actuation frequency of 100 kHz.",
keywords = "AC electrokinetic flow, Dielectrophoresis, Fluid and particles delivery, Microelectrode array",
author = "Daniel Lee and Guolin Xu and Tay, \{Hong Kiat\} and Chun Yang and Ying, \{Jackie Y.\}",
year = "2007",
doi = "10.1117/12.695598",
language = "English",
isbn = "0819465232",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
booktitle = "Micro- and Nanotechnology",
note = "Micro- and Nanotechnology: Materials, Processes, Packaging, and Systems III ; Conference date: 11-12-2006 Through 13-12-2006",
}