Abstract
A simple specific method for the determination of vitamin C has been investigated by elucidating the reaction mechanism of its oxidation with cerium(IV) in sulphuric acid media. The reaction kinetics and rate measurements which form the basis of this method were determined by following the decrease of the intense yellow colour of cerium(IV) at 405 nm. The fixed-time and fixed-concentration methods were investigated. The former was found to be more precise and was consequently used for the determination. Advantages of this method over the B.P. and other methods are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 345-351 |
| Number of pages | 7 |
| Journal | Journal of Pharmaceutical and Biomedical Analysis |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1990 |
Keywords
- Mechanism
- fixed-concentration method
- fixed-time method
- kinetics
- vitamin C and cerium(IV).
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmaceutical Science
- Drug Discovery
- Spectroscopy
- Clinical Biochemistry