Lactonization of Unsaturated Alcohols Catalyzed by Palladium Complexes under Neutral Conditions

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Abstract

Secondary and tertiary allylic alcohols react with carbon monoxide in the presence of catalytic quantities of bis(dibenzylideneacetone)palladium(0) and 1,4-bis(diphenylphosphino)butane affording lactones in 45-92% isolated yields. α,β-Unsaturated acids are formed by isomerization and carbonylation of primary allylic alcohols. 2-(5H)-Furanones were isolated in yields of 60-80% when alkynols were employed as substrates for the cyclo-carbonylation process.

Original languageEnglish
Pages (from-to)5357-5360
Number of pages4
JournalJournal of Organic Chemistry
Volume56
Issue number18
DOIs
StatePublished - 1 Aug 1991
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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