Kinetic determination of sotalol by oxidation with sodium vanadate

Salah M. Sultan; A. M. Bukhari; Herman Perzanowski

doi:10.1016/0731-7085(90)80081-Y

Kinetic determination of sotalol by oxidation with sodium vanadate

Salah M. Sultan^*, A. M. Bukhari, Herman Perzanowski

^*Corresponding author for this work

King Fahd University of Petroleum & Minerals

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90°C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.

Original language	English
Pages (from-to)	569-571
Number of pages	3
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	8
Issue number	7
DOIs	https://doi.org/10.1016/0731-7085(90)80081-Y
State	Published - 1990

Keywords

Drugs
fixed-time method.
kinetic method
sodium vanadate
sotalol

ASJC Scopus subject areas

Analytical Chemistry
Pharmaceutical Science
Drug Discovery
Spectroscopy
Clinical Biochemistry

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10.1016/0731-7085(90)80081-Y

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title = "Kinetic determination of sotalol by oxidation with sodium vanadate",

abstract = "A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90°C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.",

keywords = "Drugs, fixed-time method., kinetic method, sodium vanadate, sotalol",

author = "Sultan, \{Salah M.\} and Bukhari, \{A. M.\} and Herman Perzanowski",

year = "1990",

doi = "10.1016/0731-7085(90)80081-Y",

language = "English",

volume = "8",

pages = "569--571",

journal = "Journal of Pharmaceutical and Biomedical Analysis",

issn = "0731-7085",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Kinetic determination of sotalol by oxidation with sodium vanadate

AU - Sultan, Salah M.

AU - Bukhari, A. M.

AU - Perzanowski, Herman

PY - 1990

Y1 - 1990

N2 - A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90°C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.

AB - A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90°C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.

KW - Drugs

KW - fixed-time method.

KW - kinetic method

KW - sodium vanadate

KW - sotalol

UR - https://www.scopus.com/pages/publications/0025663818

U2 - 10.1016/0731-7085(90)80081-Y

DO - 10.1016/0731-7085(90)80081-Y

M3 - Article

C2 - 2100218

AN - SCOPUS:0025663818

SN - 0731-7085

VL - 8

SP - 569

EP - 571

JO - Journal of Pharmaceutical and Biomedical Analysis

JF - Journal of Pharmaceutical and Biomedical Analysis

IS - 7

ER -

Kinetic determination of sotalol by oxidation with sodium vanadate

Abstract

Keywords

ASJC Scopus subject areas

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