Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors

Trever Todd; Zipeng Zhen; Wei Tang; Hongmin Chen; Geoffrey Wang; Yen Jun Chuang; Kayley Deaton; Zhengwei Pan; Jin Xie

doi:10.1039/c3nr05623f

Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors

Trever Todd
, Zipeng Zhen
, Wei Tang
, Hongmin Chen
, Geoffrey Wang
, Yen Jun Chuang
, Kayley Deaton
, Zhengwei Pan
, Jin Xie^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.

Original language	English
Pages (from-to)	2073-2076
Number of pages	4
Journal	Nanoscale
Volume	6
Issue number	4
DOIs	https://doi.org/10.1039/c3nr05623f
State	Published - 21 Feb 2014
Externally published	Yes

ASJC Scopus subject areas

General Materials Science

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title = "Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors",

abstract = "Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.",

author = "Trever Todd and Zipeng Zhen and Wei Tang and Hongmin Chen and Geoffrey Wang and Chuang, \{Yen Jun\} and Kayley Deaton and Zhengwei Pan and Jin Xie",

year = "2014",

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day = "21",

doi = "10.1039/c3nr05623f",

language = "English",

volume = "6",

pages = "2073--2076",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors

AU - Todd, Trever

AU - Zhen, Zipeng

AU - Tang, Wei

AU - Chen, Hongmin

AU - Wang, Geoffrey

AU - Chuang, Yen Jun

AU - Deaton, Kayley

AU - Pan, Zhengwei

AU - Xie, Jin

PY - 2014/2/21

Y1 - 2014/2/21

N2 - Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.

AB - Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.

UR - https://www.scopus.com/pages/publications/84893274195

U2 - 10.1039/c3nr05623f

DO - 10.1039/c3nr05623f

M3 - Article

C2 - 24424277

AN - SCOPUS:84893274195

SN - 2040-3364

VL - 6

SP - 2073

EP - 2076

JO - Nanoscale

JF - Nanoscale

IS - 4

ER -

Iron oxide nanoparticle encapsulated diatoms for magnetic delivery of small molecules to tumors

Abstract

ASJC Scopus subject areas

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