Abstract
We report a novel micro fabricated thin film Ag/AgCl reference electrode (RE) coated with 6-mercepto-1-hexanol (MCH) that enables the highly stable and instant measurement of surface potential and miniaturization of the biosensing device. Integration of this RE into a compact microelectrofluidic device allows us the rapid detection of miRNA with a low concentration requiring a small sample volume (20 μL). A small-scale analog circuit for measurement, and polydimethylsiloxane (PDMS) made microfluidic channels are attached on the bottom, and the top of the electrodes respectively in a way that the device can be used multiple times with only replacing the electrodes.
| Original language | English |
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| Title of host publication | MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1689-1691 |
| Number of pages | 3 |
| ISBN (Electronic) | 9780979806483 |
| State | Published - 2015 |
| Externally published | Yes |
| Event | 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of Duration: 25 Oct 2015 → 29 Oct 2015 |
Publication series
| Name | MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 |
|---|---|
| Country/Territory | Korea, Republic of |
| City | Gyeongju |
| Period | 25/10/15 → 29/10/15 |
Bibliographical note
Publisher Copyright:© 15CBMS-0001.
Keywords
- Alkane thiol
- MiRNA
- Microelectrofluidic device
- Microfabricated reference electrode
ASJC Scopus subject areas
- Control and Systems Engineering