In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants

Erfan Salahinejad; Mohammad Jafar Hadianfard; Digby Donald Macdonald; Samin Sharifi-Asl; Masoud Mozafari; Kenneth J. Walker; Armin Tahmasbi Rad; Sundararajan V. Madihally; Lobat Tayebi

doi:10.1371/journal.pone.0061633

In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants

Erfan Salahinejad, Mohammad Jafar Hadianfard, Digby Donald Macdonald, Samin Sharifi-Asl, Masoud Mozafari, Kenneth J. Walker, Armin Tahmasbi Rad, Sundararajan V. Madihally, Lobat Tayebi^*

^*Corresponding author for this work

King Fahd University of Petroleum & Minerals

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.

Original language	English
Article number	e61633
Journal	PLoS ONE
Volume	8
Issue number	4
DOIs	https://doi.org/10.1371/journal.pone.0061633
State	Published - 22 Apr 2013

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title = "In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants",

abstract = "The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.",

author = "Erfan Salahinejad and Hadianfard, \{Mohammad Jafar\} and Macdonald, \{Digby Donald\} and Samin Sharifi-Asl and Masoud Mozafari and Walker, \{Kenneth J.\} and Rad, \{Armin Tahmasbi\} and Madihally, \{Sundararajan V.\} and Lobat Tayebi",

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T1 - In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants

AU - Salahinejad, Erfan

AU - Hadianfard, Mohammad Jafar

AU - Macdonald, Digby Donald

AU - Sharifi-Asl, Samin

AU - Mozafari, Masoud

AU - Walker, Kenneth J.

AU - Rad, Armin Tahmasbi

AU - Madihally, Sundararajan V.

AU - Tayebi, Lobat

PY - 2013/4/22

Y1 - 2013/4/22

N2 - The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.

AB - The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.

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JO - PLoS ONE

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M1 - e61633

ER -

In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants

Abstract

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