Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI

Khuhed Memon; Norashikin Yahya; Mohd Zuki Yusoff; Hilwati Hashim; Syed Saad Azhar Ali; Shahabuddin Siddiqui

doi:10.1109/ViTECoN58111.2023.10157177

Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI

Khuhed Memon, Norashikin Yahya, Mohd Zuki Yusoff, Hilwati Hashim, Syed Saad Azhar Ali, Shahabuddin Siddiqui

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Multiple sclerosis (MS) is a type of auto-immune disease affecting the human brain. One of the challenges in clinical diagnosis of MS lies in its close similarity to another type of brain auto-immune disease known as neuromyelitis optica (MNO). Hence, various researchers are looking into the development of computer-aided differential diagnosis (CADD) of MS vs. MNO. Generally, the development of the CADD, involves image pre-processing, feature extraction, statistical analysis and training and testing of the classification model. The focus of this paper is on the 2 critical pre-processing steps prior to classification of MS vs. MNO, namely skull stripping and lesion segmentation. In particular, both skull stripping and brain lesion segmentation are tested with a popular semantic segmentation technique, DeepLabV3. For comparison, a recently published technique, SynthStrip from FreeSurfer [1], developed by Harvard University is also tested for brain extraction / skull removal. Similarly for segmentation of brain lesions, Lesion Segmentation Tool in SPM Toolbox is tested and compared. The results from this study provides insight on what are the appropriate pre-processing techniques for the development of an reliable automatic differential diagnosis tool for multiple sclerosis conditions.

Original language	English
Title of host publication	ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings
Editors	Thanikaiselvan V Thanikaiselvan V, Renuga Devi S, Shankar T, Kalaivani S
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9798350347982
DOIs	https://doi.org/10.1109/ViTECoN58111.2023.10157177
State	Published - 2023
Event	2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, ViTECoN 2023 - Vellore, India Duration: 5 May 2023 → 6 May 2023

Publication series

Name	ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings

Conference

Conference	2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, ViTECoN 2023
Country/Territory	India
City	Vellore
Period	5/05/23 → 6/05/23

Bibliographical note

Publisher Copyright:
© 2023 IEEE.

Keywords

Brain MRI
Computer-Aided Diagnosis
DeepLabV3
Neurological disorders
Neuromyelitis Optica

ASJC Scopus subject areas

Artificial Intelligence
Computer Networks and Communications
Computer Science Applications
Hardware and Architecture
Instrumentation

Access to Document

10.1109/ViTECoN58111.2023.10157177

Cite this

Memon, K., Yahya, N., Yusoff, M. Z., Hashim, H., Ali, S. S. A., & Siddiqui, S. (2023). Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI. In T. V. Thanikaiselvan V, R. D. S, S. T, & K. S (Eds.), ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings (ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ViTECoN58111.2023.10157177

Memon, Khuhed ; Yahya, Norashikin ; Yusoff, Mohd Zuki et al. / Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI. ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings. editor / Thanikaiselvan V Thanikaiselvan V ; Renuga Devi S ; Shankar T ; Kalaivani S. Institute of Electrical and Electronics Engineers Inc., 2023. (ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings).

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title = "Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI",

abstract = "Multiple sclerosis (MS) is a type of auto-immune disease affecting the human brain. One of the challenges in clinical diagnosis of MS lies in its close similarity to another type of brain auto-immune disease known as neuromyelitis optica (MNO). Hence, various researchers are looking into the development of computer-aided differential diagnosis (CADD) of MS vs. MNO. Generally, the development of the CADD, involves image pre-processing, feature extraction, statistical analysis and training and testing of the classification model. The focus of this paper is on the 2 critical pre-processing steps prior to classification of MS vs. MNO, namely skull stripping and lesion segmentation. In particular, both skull stripping and brain lesion segmentation are tested with a popular semantic segmentation technique, DeepLabV3. For comparison, a recently published technique, SynthStrip from FreeSurfer [1], developed by Harvard University is also tested for brain extraction / skull removal. Similarly for segmentation of brain lesions, Lesion Segmentation Tool in SPM Toolbox is tested and compared. The results from this study provides insight on what are the appropriate pre-processing techniques for the development of an reliable automatic differential diagnosis tool for multiple sclerosis conditions.",

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author = "Khuhed Memon and Norashikin Yahya and Yusoff, {Mohd Zuki} and Hilwati Hashim and Ali, {Syed Saad Azhar} and Shahabuddin Siddiqui",

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year = "2023",

doi = "10.1109/ViTECoN58111.2023.10157177",

language = "English",

series = "ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

editor = "{Thanikaiselvan V}, {Thanikaiselvan V} and S, {Renuga Devi} and Shankar T and Kalaivani S",

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Memon, K, Yahya, N, Yusoff, MZ, Hashim, H, Ali, SSA & Siddiqui, S 2023, Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI. in TV Thanikaiselvan V, RD S, S T & K S (eds), ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings. ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings, Institute of Electrical and Electronics Engineers Inc., 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, ViTECoN 2023, Vellore, India, 5/05/23. https://doi.org/10.1109/ViTECoN58111.2023.10157177

Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI. / Memon, Khuhed; Yahya, Norashikin; Yusoff, Mohd Zuki et al.
ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings. ed. / Thanikaiselvan V Thanikaiselvan V; Renuga Devi S; Shankar T; Kalaivani S. Institute of Electrical and Electronics Engineers Inc., 2023. (ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Memon, Khuhed

AU - Yahya, Norashikin

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AU - Siddiqui, Shahabuddin

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Memon K, Yahya N, Yusoff MZ, Hashim H, Ali SSA, Siddiqui S. Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI. In Thanikaiselvan V TV, S RD, T S, S K, editors, ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings. Institute of Electrical and Electronics Engineers Inc. 2023. (ViTECoN 2023 - 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, Proceedings). doi: 10.1109/ViTECoN58111.2023.10157177

Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI

Abstract

Publication series

Conference

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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