Highly Enantioselective Conjugate Addition of Glycine Imines to Activated Alkenes Catalyzed by Amino-Acid-Derived Chiral Phosphonium Salts

Shan Wen; Xing Li; Weijun Yao; Abdul Waheed; Nisar Ullah; Yixin Lu

doi:10.1002/ejoc.201600794

Highly Enantioselective Conjugate Addition of Glycine Imines to Activated Alkenes Catalyzed by Amino-Acid-Derived Chiral Phosphonium Salts

Shan Wen, Xing Li, Weijun Yao, Abdul Waheed, Nisar Ullah^*, Yixin Lu

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Chiral quaternary phosphonium salts derived from amino acids were readily prepared and employed as phase-transfer catalysts for the highly enantioselective conjugate addition of glycine imines to various activated alkenes, including chalcones, acrylates, and vinyl ketones.

Original language	English
Pages (from-to)	4298-4301
Number of pages	4
Journal	European Journal of Organic Chemistry
Volume	2016
Issue number	25
DOIs	https://doi.org/10.1002/ejoc.201600794
State	Published - Sep 2016

Bibliographical note

Publisher Copyright:
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

Amino acids
Asymmetric synthesis
Conjugate addition
Phase-transfer catalysis
Phosphonium salts

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/ejoc.201600794

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title = "Highly Enantioselective Conjugate Addition of Glycine Imines to Activated Alkenes Catalyzed by Amino-Acid-Derived Chiral Phosphonium Salts",

abstract = "Chiral quaternary phosphonium salts derived from amino acids were readily prepared and employed as phase-transfer catalysts for the highly enantioselective conjugate addition of glycine imines to various activated alkenes, including chalcones, acrylates, and vinyl ketones.",

keywords = "Amino acids, Asymmetric synthesis, Conjugate addition, Phase-transfer catalysis, Phosphonium salts",

author = "Shan Wen and Xing Li and Weijun Yao and Abdul Waheed and Nisar Ullah and Yixin Lu",

note = "Publisher Copyright: {\textcopyright} 2016 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2016",

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doi = "10.1002/ejoc.201600794",

language = "English",

volume = "2016",

pages = "4298--4301",

journal = "European Journal of Organic Chemistry",

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publisher = "Wiley-VCH Verlag",

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T1 - Highly Enantioselective Conjugate Addition of Glycine Imines to Activated Alkenes Catalyzed by Amino-Acid-Derived Chiral Phosphonium Salts

AU - Wen, Shan

AU - Li, Xing

AU - Yao, Weijun

AU - Waheed, Abdul

AU - Ullah, Nisar

AU - Lu, Yixin

PY - 2016/9

Y1 - 2016/9

N2 - Chiral quaternary phosphonium salts derived from amino acids were readily prepared and employed as phase-transfer catalysts for the highly enantioselective conjugate addition of glycine imines to various activated alkenes, including chalcones, acrylates, and vinyl ketones.

AB - Chiral quaternary phosphonium salts derived from amino acids were readily prepared and employed as phase-transfer catalysts for the highly enantioselective conjugate addition of glycine imines to various activated alkenes, including chalcones, acrylates, and vinyl ketones.

KW - Amino acids

KW - Asymmetric synthesis

KW - Conjugate addition

KW - Phase-transfer catalysis

KW - Phosphonium salts

UR - https://www.scopus.com/pages/publications/84985905557

U2 - 10.1002/ejoc.201600794

DO - 10.1002/ejoc.201600794

M3 - Article

AN - SCOPUS:84985905557

SN - 1434-193X

VL - 2016

SP - 4298

EP - 4301

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 25

ER -

Highly Enantioselective Conjugate Addition of Glycine Imines to Activated Alkenes Catalyzed by Amino-Acid-Derived Chiral Phosphonium Salts

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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