High-dose monoclonal antibodies via the subcutaneous route: Challenges and technical solutions, an industry perspective

Chakravarthy Narasimhan, Henryk MacH, Mohammed Shameem*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations

Abstract

This review summarizes the various challenges in product development involved in subcutaneous administration of high-dose monoclonal antibodies and attempts to provide an industry perspective of some of the available technologies and potential avenues to overcome these challenges.

Original languageEnglish
Pages (from-to)889-900
Number of pages12
JournalTherapeutic Delivery
Volume3
Issue number7
DOIs
StatePublished - Jul 2012
Externally publishedYes

ASJC Scopus subject areas

  • Pharmaceutical Science

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