Heat transfer analysis on peristaltically driven motion of particle-fluid suspension in Newtonian fluid using curvilinear coordinates bounded by slip boundary: Applications in drug delivery through blood vessels

The heat transfer analysis of peristaltic flow with particle-fluid suspension of Newtonian fluid is carried out. The fluid is passing through the curved channel, and the walls of the channel exhibit wavy features for fluid passage. Furthermore, this study incorporates the slip effects on boundary conditions. To make the system steady, the unsteady coordinates are transformed into wave frame coordinates. The supposition of long wavelength along with low Reynolds number is used to obtain analytical solutions for the velocity and the thermal distribution of both phases, the mean flow rates, and the pressure gradient. The pressure rise is evaluated using a numerical approach. The graphs for various parameters are drawn to analyze their impact on velocity and temperature of both phases. It is observed that temperature significantly affects biofluid dynamics, primarily by influencing the viscosity of fluids like blood and other biological fluids. Higher temperatures generally reduce viscosity, leading to increased flow rates. This is because increased thermal energy allows molecules to move more freely, reducing the resistance to flow. This investigation also provides a deeper understanding of the interaction between fluid and solid particles, offering advancements in both theoretical modeling and practical pharmaceutical systems, with direct applications in drug delivery through blood vessels.