Furoquinoline alkaloids from Teclea nobilis

Adnan J. Al-Rehailya; Mohammad S. Ahmad; Ilias Muhammad; Assad A. Al-Thukair; Herman P. Perzanowski

doi:10.1016/j.phytochem.2003.09.013

Furoquinoline alkaloids from Teclea nobilis

Adnan J. Al-Rehailya^*
, Mohammad S. Ahmad
, Ilias Muhammad
, Assad A. Al-Thukair
, Herman P. Perzanowski

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Five new furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1-5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.

Original language	English
Pages (from-to)	1405-1411
Number of pages	7
Journal	Phytochemistry
Volume	64
Issue number	8
DOIs	https://doi.org/10.1016/j.phytochem.2003.09.013
State	Published - Dec 2003

Bibliographical note

Funding Information:
The authors sincerely thank Dr. Charles D. Hufford and Mr. Frank M. Wiggers, University of Mississippi, and Dr. Farouk S. El-Feraly, KSU, for NMR spectra, Dr. D. Chuck Dunbar for HRMS, and Dr. Melissa R. Jacob, Ms. Sharon Sanders and Mr. John Trott for technical assistances. The School of Pharmacy, UM, author acknowledges the financial support provided in part by the United States Department of Agriculture ARS Specific Cooperative Agreement No. 58-6408-2-0009.

Keywords

Alkaloids
Chlorodesnkolbisine
Furoquinoline
Isotecleoxine
Methylnkolbisine
Rutaceae
Teclea nobilis
Tecleabine
Tecleoxine

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/j.phytochem.2003.09.013

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@article{9238223b570c4c159643b4a95bc3a948,

title = "Furoquinoline alkaloids from Teclea nobilis",

abstract = "Five new furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1-5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.",

keywords = "Alkaloids, Chlorodesnkolbisine, Furoquinoline, Isotecleoxine, Methylnkolbisine, Rutaceae, Teclea nobilis, Tecleabine, Tecleoxine",

author = "Al-Rehailya, \{Adnan J.\} and Ahmad, \{Mohammad S.\} and Ilias Muhammad and Al-Thukair, \{Assad A.\} and Perzanowski, \{Herman P.\}",

note = "Funding Information: The authors sincerely thank Dr. Charles D. Hufford and Mr. Frank M. Wiggers, University of Mississippi, and Dr. Farouk S. El-Feraly, KSU, for NMR spectra, Dr. D. Chuck Dunbar for HRMS, and Dr. Melissa R. Jacob, Ms. Sharon Sanders and Mr. John Trott for technical assistances. The School of Pharmacy, UM, author acknowledges the financial support provided in part by the United States Department of Agriculture ARS Specific Cooperative Agreement No. 58-6408-2-0009.",

year = "2003",

month = dec,

doi = "10.1016/j.phytochem.2003.09.013",

language = "English",

volume = "64",

pages = "1405--1411",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Ltd.",

number = "8",

}

TY - JOUR

T1 - Furoquinoline alkaloids from Teclea nobilis

AU - Al-Rehailya, Adnan J.

AU - Ahmad, Mohammad S.

AU - Muhammad, Ilias

AU - Al-Thukair, Assad A.

AU - Perzanowski, Herman P.

N1 - Funding Information: The authors sincerely thank Dr. Charles D. Hufford and Mr. Frank M. Wiggers, University of Mississippi, and Dr. Farouk S. El-Feraly, KSU, for NMR spectra, Dr. D. Chuck Dunbar for HRMS, and Dr. Melissa R. Jacob, Ms. Sharon Sanders and Mr. John Trott for technical assistances. The School of Pharmacy, UM, author acknowledges the financial support provided in part by the United States Department of Agriculture ARS Specific Cooperative Agreement No. 58-6408-2-0009.

PY - 2003/12

Y1 - 2003/12

N2 - Five new furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1-5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.

AB - Five new furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1-5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.

KW - Alkaloids

KW - Chlorodesnkolbisine

KW - Furoquinoline

KW - Isotecleoxine

KW - Methylnkolbisine

KW - Rutaceae

KW - Teclea nobilis

KW - Tecleabine

KW - Tecleoxine

UR - https://www.scopus.com/pages/publications/0344010632

U2 - 10.1016/j.phytochem.2003.09.013

DO - 10.1016/j.phytochem.2003.09.013

M3 - Article

C2 - 14630007

AN - SCOPUS:0344010632

SN - 0031-9422

VL - 64

SP - 1405

EP - 1411

JO - Phytochemistry

JF - Phytochemistry

IS - 8

ER -

Furoquinoline alkaloids from Teclea nobilis

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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