Abstract
Curcumin nanoparticles)Cur/GANPs(were formulated based on gum arabic)GA(as a stabilizer coatings for nanoparticles through efficient synthesis approach . The current study investigated the antioxidant properties and antihypertensive activity of curcumin)Cur(using various established in vitro assays, such as 1,1-diphenyl-2-picrylhydrazyl)DPPH(as well as angiotensin converting enzyme (ACE(inhibitory activity. The in vitro cytotoxicity of Cur/GANPs against human liver cancer)HepG2(, and colon cancer)HT29(was investigated. The exposure of human cancer cells to Cur/GANPs)1.56-100 µg/ml(using MTT)3-)4,5-dimethylthiazol-2-yl(2,5-diphenyl tetrazolium bromide(has revealed that the Cur/GANPs inhibited the growth of cell lines examined in a dose dependent manner. Hence, Cur/GANPs nanoparticles may have great potential to be applied for cancer treatment.
| Original language | English |
|---|---|
| Article number | 012101 |
| Journal | IOP Conference Series: Materials Science and Engineering |
| Volume | 991 |
| Issue number | 1 |
| DOIs | |
| State | Published - 22 Dec 2020 |
| Externally published | Yes |
| Event | 5th International Conference of Chemical Engineering and Industrial Biotechnology, ICCEIB 2020 - Kuala Lumpur, Malaysia Duration: 9 Aug 2020 → 11 Aug 2020 |
Bibliographical note
Publisher Copyright:© 2020 Institute of Physics Publishing. All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- General Materials Science
- General Engineering
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