Abstract
Much attention has been devoted to the synthesis and antimicrobial studies of nanopatterned surfaces. However, factors contributing to their potential and eventual application, such as large-scale synthesis, material durability, and biocompatibility, are often neglected in such studies. In this paper, the ZnO nanopillar surface is found to be amenable to synthesis in large forms and stable upon exposure to highly accelerated lifetime tests (HALT) without any detrimental effect on its antimicrobial activity. Additionally, the material is effective against clinically isolated pathogens and biocompatible in vivo. These findings illustrate the broad applicability of ZnO nanopillar surfaces in the common equipment used in health-care and consumer industries.
| Original language | English |
|---|---|
| Pages (from-to) | 7524-7531 |
| Number of pages | 8 |
| Journal | ACS Applied Bio Materials |
| Volume | 4 |
| Issue number | 10 |
| DOIs | |
| State | Published - 18 Oct 2021 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2021 American Chemical Society.
Keywords
- antimicrobial materials
- durability
- nanopillar surfaces
- reactive oxygen species
- zinc oxide
ASJC Scopus subject areas
- Biomaterials
- General Chemistry
- Biomedical Engineering
- Biochemistry, medical