Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO4) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol)

Selvarasu Maheshwaran; Muthumariappan Akilarasan; Tse Wei Chen; Shen Ming Chen; Elayappan Tamilalagan; Ting Yu Jiang; Eman A. Alabdullkarem; Mustafa Soylak

doi:10.1007/s00604-021-04758-5

Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO₄) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol)

Selvarasu Maheshwaran, Muthumariappan Akilarasan, Tse Wei Chen, Shen Ming Chen^*, Elayappan Tamilalagan, Ting Yu Jiang, Eman A. Alabdullkarem, Mustafa Soylak^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Metastable and rarely reported GO warped tetragonal phase t-lanthanum vanadate nanocomposites (GO@LaVO₄-NCs) are reported for the sensitive electrochemical determination of antifungal drug Clioquinol (CQ). The hydrothermal method was adopted for synthesis of GO@LaVO₄-NCs. The electrochemical performance of CQ was examined using cyclic voltammetry (CV) and differential plus voltammetry (DPV) at GO@LaVO₄-NCs modified glassy carbon electrode (GCE). The electrocatalytic oxidation of CQ at the GO@LaVO₄-NCs/GCE shows the highest anodic peak current at a potential of +0.51 V vs. Ag/AgCl. The proposed sensor provides excellent sensitivity of 4.1894 μA μM⁻¹ cm⁻², a very low detection limit (LOD) of 2.44 nM, and a wide range of 25 nM to 438.52 μM towards CQ detection. Finally, the detection of CQ in biological media was successfully done using the GO@LaVO₄-NCs/GCE and possesses recoveries of 94.67–98.0%. Graphical abstract: [Figure not available: see fulltext.]

Original language	English
Article number	102
Journal	Microchimica Acta
Volume	188
Issue number	3
DOIs	https://doi.org/10.1007/s00604-021-04758-5
State	Published - Mar 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature.

Keywords

Anti-fungal drug determination
Clioquinol detection
Cyclic voltammetry
Differential pulse voltammetry
Electrochemical sensor
GO@LaVO nanocomposites
Modified glassy carbon electrode

ASJC Scopus subject areas

Analytical Chemistry

Access to Document

10.1007/s00604-021-04758-5

Cite this

Maheshwaran, S., Akilarasan, M., Chen, T. W., Chen, S. M., Tamilalagan, E., Jiang, T. Y., Alabdullkarem, E. A., & Soylak, M. (2021). Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO₄) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol). Microchimica Acta, 188(3), Article 102. https://doi.org/10.1007/s00604-021-04758-5

@article{7904a66b9692475883ec2d783df6e55f,

title = "Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO4) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol)",

abstract = "Metastable and rarely reported GO warped tetragonal phase t-lanthanum vanadate nanocomposites (GO@LaVO4-NCs) are reported for the sensitive electrochemical determination of antifungal drug Clioquinol (CQ). The hydrothermal method was adopted for synthesis of GO@LaVO4-NCs. The electrochemical performance of CQ was examined using cyclic voltammetry (CV) and differential plus voltammetry (DPV) at GO@LaVO4-NCs modified glassy carbon electrode (GCE). The electrocatalytic oxidation of CQ at the GO@LaVO4-NCs/GCE shows the highest anodic peak current at a potential of +0.51 V vs. Ag/AgCl. The proposed sensor provides excellent sensitivity of 4.1894 μA μM−1 cm−2, a very low detection limit (LOD) of 2.44 nM, and a wide range of 25 nM to 438.52 μM towards CQ detection. Finally, the detection of CQ in biological media was successfully done using the GO@LaVO4-NCs/GCE and possesses recoveries of 94.67–98.0\%. Graphical abstract: [Figure not available: see fulltext.]",

keywords = "Anti-fungal drug determination, Clioquinol detection, Cyclic voltammetry, Differential pulse voltammetry, Electrochemical sensor, GO@LaVO nanocomposites, Modified glassy carbon electrode",

author = "Selvarasu Maheshwaran and Muthumariappan Akilarasan and Chen, \{Tse Wei\} and Chen, \{Shen Ming\} and Elayappan Tamilalagan and Jiang, \{Ting Yu\} and Alabdullkarem, \{Eman A.\} and Mustafa Soylak",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature.",

year = "2021",

month = mar,

doi = "10.1007/s00604-021-04758-5",

language = "English",

volume = "188",

journal = "Microchimica Acta",

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Maheshwaran, S, Akilarasan, M, Chen, TW, Chen, SM, Tamilalagan, E, Jiang, TY, Alabdullkarem, EA & Soylak, M 2021, 'Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO₄) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol)', Microchimica Acta, vol. 188, no. 3, 102. https://doi.org/10.1007/s00604-021-04758-5

Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO₄) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol). / Maheshwaran, Selvarasu; Akilarasan, Muthumariappan; Chen, Tse Wei et al.
In: Microchimica Acta, Vol. 188, No. 3, 102, 03.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Electrocatalytic evaluation of graphene oxide warped tetragonal t-lanthanum vanadate (GO@LaVO4) nanocomposites for the voltammetric detection of antifungal and antiprotozoal drug (clioquinol)

AU - Maheshwaran, Selvarasu

AU - Akilarasan, Muthumariappan

AU - Chen, Tse Wei

AU - Chen, Shen Ming

AU - Tamilalagan, Elayappan

AU - Jiang, Ting Yu

AU - Alabdullkarem, Eman A.

AU - Soylak, Mustafa

PY - 2021/3

Y1 - 2021/3

N2 - Metastable and rarely reported GO warped tetragonal phase t-lanthanum vanadate nanocomposites (GO@LaVO4-NCs) are reported for the sensitive electrochemical determination of antifungal drug Clioquinol (CQ). The hydrothermal method was adopted for synthesis of GO@LaVO4-NCs. The electrochemical performance of CQ was examined using cyclic voltammetry (CV) and differential plus voltammetry (DPV) at GO@LaVO4-NCs modified glassy carbon electrode (GCE). The electrocatalytic oxidation of CQ at the GO@LaVO4-NCs/GCE shows the highest anodic peak current at a potential of +0.51 V vs. Ag/AgCl. The proposed sensor provides excellent sensitivity of 4.1894 μA μM−1 cm−2, a very low detection limit (LOD) of 2.44 nM, and a wide range of 25 nM to 438.52 μM towards CQ detection. Finally, the detection of CQ in biological media was successfully done using the GO@LaVO4-NCs/GCE and possesses recoveries of 94.67–98.0%. Graphical abstract: [Figure not available: see fulltext.]

AB - Metastable and rarely reported GO warped tetragonal phase t-lanthanum vanadate nanocomposites (GO@LaVO4-NCs) are reported for the sensitive electrochemical determination of antifungal drug Clioquinol (CQ). The hydrothermal method was adopted for synthesis of GO@LaVO4-NCs. The electrochemical performance of CQ was examined using cyclic voltammetry (CV) and differential plus voltammetry (DPV) at GO@LaVO4-NCs modified glassy carbon electrode (GCE). The electrocatalytic oxidation of CQ at the GO@LaVO4-NCs/GCE shows the highest anodic peak current at a potential of +0.51 V vs. Ag/AgCl. The proposed sensor provides excellent sensitivity of 4.1894 μA μM−1 cm−2, a very low detection limit (LOD) of 2.44 nM, and a wide range of 25 nM to 438.52 μM towards CQ detection. Finally, the detection of CQ in biological media was successfully done using the GO@LaVO4-NCs/GCE and possesses recoveries of 94.67–98.0%. Graphical abstract: [Figure not available: see fulltext.]

KW - Anti-fungal drug determination

KW - Clioquinol detection

KW - Cyclic voltammetry

KW - Differential pulse voltammetry

KW - Electrochemical sensor

KW - GO@LaVO nanocomposites

KW - Modified glassy carbon electrode

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U2 - 10.1007/s00604-021-04758-5

DO - 10.1007/s00604-021-04758-5

M3 - Article

C2 - 33638711

AN - SCOPUS:85101975902

SN - 0026-3672

VL - 188

JO - Microchimica Acta

JF - Microchimica Acta

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M1 - 102

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