Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce

Sana Kabdrakhmanova; Robin Augustine; Aiswarya Sathian; Annu Thomas; Tomy Muringayil Joseph; Nandakumar Kalarikkal; Zhanar Ibraeva; Beisebekov Madiyar; Sabu Thomas; Anwarul Hasan; K. S. Joshy

doi:10.1002/pol.20240498

Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce

Sana Kabdrakhmanova
, Robin Augustine
, Aiswarya Sathian
, Annu Thomas
, Tomy Muringayil Joseph
, Nandakumar Kalarikkal
, Zhanar Ibraeva
, Beisebekov Madiyar
, Sabu Thomas
, Anwarul Hasan^*
, K. S. Joshy^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.

Original language	English
Pages (from-to)	5414-5425
Number of pages	12
Journal	Journal of Polymer Science
Volume	63
Issue number	24
DOIs	https://doi.org/10.1002/pol.20240498
State	Published - 15 Dec 2025
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2025 Wiley Periodicals LLC.

Keywords

curcumin
dextran
nano-coating
nanodispersion

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Polymers and Plastics
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/pol.20240498

Cite this

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title = "Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce",

abstract = "The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.",

keywords = "curcumin, dextran, nano-coating, nanodispersion",

author = "Sana Kabdrakhmanova and Robin Augustine and Aiswarya Sathian and Annu Thomas and Joseph, \{Tomy Muringayil\} and Nandakumar Kalarikkal and Zhanar Ibraeva and Beisebekov Madiyar and Sabu Thomas and Anwarul Hasan and Joshy, \{K. S.\}",

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year = "2025",

month = dec,

day = "15",

doi = "10.1002/pol.20240498",

language = "English",

volume = "63",

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journal = "Journal of Polymer Science",

issn = "2642-4150",

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TY - JOUR

T1 - Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce

AU - Kabdrakhmanova, Sana

AU - Augustine, Robin

AU - Sathian, Aiswarya

AU - Thomas, Annu

AU - Joseph, Tomy Muringayil

AU - Kalarikkal, Nandakumar

AU - Ibraeva, Zhanar

AU - Madiyar, Beisebekov

AU - Thomas, Sabu

AU - Hasan, Anwarul

AU - Joshy, K. S.

PY - 2025/12/15

Y1 - 2025/12/15

N2 - The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.

AB - The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.

KW - curcumin

KW - dextran

KW - nano-coating

KW - nanodispersion

UR - https://www.scopus.com/pages/publications/85214449080

U2 - 10.1002/pol.20240498

DO - 10.1002/pol.20240498

M3 - Article

AN - SCOPUS:85214449080

SN - 2642-4150

VL - 63

SP - 5414

EP - 5425

JO - Journal of Polymer Science

JF - Journal of Polymer Science

IS - 24

ER -

Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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Cite this