Abstract
Since its development in 2006, dispersive liquid-liquid microextraction has witnessed many improvements in the design of extraction devices, extractant dispersion strategies, choice of extraction and dispersive solvents, and phase separation approaches. It has also been combined with other extraction techniques to extend its application to more complicated matrices. Many developments have been made concerning simultaneous derivatization, entire procedure automation, and coupling with analytical instrumentation. The main objective of these changes was to resolve a certain issue with the existing design or procedure or make the extraction process and analysis relatively easier, faster, or greener. This review aims to provide an overview of the evolution of DLLME over the years and highlights the scenarios where different formats can be applied, and their advantages and limitations have been critically appraised.
| Original language | English |
|---|---|
| Article number | 116636 |
| Journal | TrAC - Trends in Analytical Chemistry |
| Volume | 152 |
| DOIs | |
| State | Published - Jul 2022 |
Bibliographical note
Publisher Copyright:© 2022 Elsevier B.V.
Keywords
- DLLME
- Extraction solvents
- Green analytical chemistry
- Microextraction
- Miniaturization
- Sample preparation
ASJC Scopus subject areas
- Analytical Chemistry
- Spectroscopy