Deuterium-labeled 2′-hydroxypyridoxol

Nisar Ullah; Johannes Zeidler; Ian D. Spenser

doi:10.1055/s-2003-40355

Deuterium-labeled 2′-hydroxypyridoxol

Nisar Ullah
, Johannes Zeidler
, Ian D. Spenser^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The preparation of [5′,5′-²H₂]- and [2′,2′,5′,5′-²H₄]-2′- hydroxypyridoxol, as well as of [5′,5′-²H₂]-4-pyridoxic acid, starting from 3,4′-O-isopropylidenepyridoxol, is described. The labeled compounds were employed in an investigation of the biosynthesis of Vitamins B₁ and B₆.

Original language	English
Pages (from-to)	1344-1348
Number of pages	5
Journal	Synlett
Issue number	9 SPEC. ISS.
DOIs	https://doi.org/10.1055/s-2003-40355
State	Published - 2003
Externally published	Yes

Keywords

2′-hydroxypyridoxine
Biosynthesis
Deuterium NMR
Deuterium-labeling

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-2003-40355

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title = "Deuterium-labeled 2′-hydroxypyridoxol",

abstract = "The preparation of [5′,5′-2H2]- and [2′,2′,5′,5′-2H4]-2′- hydroxypyridoxol, as well as of [5′,5′-2H2]-4-pyridoxic acid, starting from 3,4′-O-isopropylidenepyridoxol, is described. The labeled compounds were employed in an investigation of the biosynthesis of Vitamins B1 and B6.",

keywords = "2′-hydroxypyridoxine, Biosynthesis, Deuterium NMR, Deuterium-labeling",

author = "Nisar Ullah and Johannes Zeidler and Spenser, \{Ian D.\}",

year = "2003",

doi = "10.1055/s-2003-40355",

language = "English",

pages = "1344--1348",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "9 SPEC. ISS.",

}

TY - JOUR

T1 - Deuterium-labeled 2′-hydroxypyridoxol

AU - Ullah, Nisar

AU - Zeidler, Johannes

AU - Spenser, Ian D.

PY - 2003

Y1 - 2003

N2 - The preparation of [5′,5′-2H2]- and [2′,2′,5′,5′-2H4]-2′- hydroxypyridoxol, as well as of [5′,5′-2H2]-4-pyridoxic acid, starting from 3,4′-O-isopropylidenepyridoxol, is described. The labeled compounds were employed in an investigation of the biosynthesis of Vitamins B1 and B6.

AB - The preparation of [5′,5′-2H2]- and [2′,2′,5′,5′-2H4]-2′- hydroxypyridoxol, as well as of [5′,5′-2H2]-4-pyridoxic acid, starting from 3,4′-O-isopropylidenepyridoxol, is described. The labeled compounds were employed in an investigation of the biosynthesis of Vitamins B1 and B6.

KW - 2′-hydroxypyridoxine

KW - Biosynthesis

KW - Deuterium NMR

KW - Deuterium-labeling

UR - https://www.scopus.com/pages/publications/0038103078

U2 - 10.1055/s-2003-40355

DO - 10.1055/s-2003-40355

M3 - Article

AN - SCOPUS:0038103078

SN - 0936-5214

SP - 1344

EP - 1348

JO - Synlett

JF - Synlett

IS - 9 SPEC. ISS.

ER -

Deuterium-labeled 2′-hydroxypyridoxol

Abstract

Keywords

ASJC Scopus subject areas

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